2-Oxo-1-pyrrolidinecarboxylic acid

Basic Information

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CAS Number

4042-36-8

Molecular Formula

C5H7NO3

Molecular Weight

129.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

159.0 to 164.0 deg-C

Boiling Point

453.1°C at 760 mmHg

Flash Point

227.8℃

Refractive Index

10 ° (C=5, H2O)

Specific Rotation

27.5 º (c=10,1N NaOH)

SMILES

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O=C1CC[C@H](C(O)=O)N1

InChI

InChI=1S/C5H7NO3/c7-4-2-1-3-6(4)5(8)9/h1-3H2,(H,8,9)

InChIKey

DQAKJEWZWDQURW-UHFFFAOYSA-N

LogP

-0.6504000000000001

Topological Polar Surface Area

66.39999999999999 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

154

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(R)-5-Oxopyrrolidine-2-carboxylic acid
D-5-Pyrrolidone-2-carboxylic acid
D-Pyroglutamic acid
(R)-(+)-2-Pyrrolidinone-5-carboxylic acid
H-D-Pyr-OH
(2R)-5-Oxopyrrolidine-2-carboxylic acid
(R)-(+)-2-Pyrrolidone-5-carboxylic Acid
(R)-2-Pyrrolidinone-5-carboxylic Acid
(+)-Pyroglutamic acid
(S)-(-)-2-pyrrolidone-5-carboxylic acid
5-oxo-D-proline
D-5-Oxo-2-pyrrolidinecarboxylic acid
D-pyrrolidone-5-carboxylic acid
Pyroglutamate
pyroglutamic acid
D-Glutamic Acid Lactam
(R)-2-Pyrrolidone-5-carboxylic Acid
(R)-5-Oxopyrrolidine-2-carboxylic Acid
5-Oxo-D-proline
(R)-(+)-2-Pyrrolidone-5-carboxylic acid
(2R)-5-oxopyrrolidine-2-carboxylic acid

MDL Number

MFCD00066212

FAQ

What is 2-Oxo-1-pyrrolilinecarboxylic acid (CAS: 4042-36-8)?

2-Oxo-1-pyrrolidinecarboxylic acid (4042-36-8) is an organic compound with the chemical formula C5H9NO3. It features a pyrrolidine ring with a ketone group and a carboxylic acid functional group. This compound is a white crystalline solid, soluble in water and polar organic solvents, and exhibits acidic properties due to its carboxylic acid group. It is commonly used as an intermediate in chemical synthesis.

What are the main uses of 2-Oxo-1-pyrrolidinecarboxylic acid (CAS: 4042-36-8)?

2-Oxo-1-pyrrolidinecarboxylic acid (4042-36-8) is widely applied in pharmaceuticals for synthesizing antifungal and antidepressant drugs. It also serves in industrial processes as a building block for polymers and chelating agents. In research, it is utilized for enzyme inhibition studies and organic chemistry applications. Its versatility makes it a key component in drug development and chemical innovation.

Is 2-Oxo-1-pyrrolidinecarboxylic acid (CAS: 4042-36-8) safe?

2-Oxo-1-pyrrolidinecarboxylic acid (4042-36-8) is generally considered safe when handled properly. However, it may cause skin or eye irritation and should be treated with caution. Safety standards recommend using appropriate personal protective equipment (PPE) and working in a well-ventilated area. Always consult safety data sheets (SDS) for detailed handling guidelines and toxicity information.

How should 2-Oxo-1-pyrrolidinecarboxylic acid (CAS: 4042-36-8) be stored?

2-Oxo-1-pyrrolidinecarboxylic acid (4042-36-8) should be stored in a cool, dry, and dark place, ideally at 2-8°C. Keep it in a tightly sealed container to prevent moisture absorption and degradation. Avoid exposure to air and light to maintain stability. Ensure storage conditions comply with chemical safety standards to preserve its integrity and prevent hazards.