1-(2-Iodoacetoxy)-2,5-pyrrolidinedione

Basic Information

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CAS Number

39028-27-8

Molecular Formula

C6H6INO4

Molecular Weight

283.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

146.0 to 150.0 deg-C

Boiling Point

315.6±44.0℃ at 760 mmHg

Density

2.11

Flash Point

315.6 °C at 760 mmHg

Solubility

DMF: 50 mg/mL

Refractive Index

1.614

SMILES

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C1CC(=O)N(C1=O)OC(=O)CI

InChI

InChI=1S/C6H6INO4/c7-3-6(11)12-8-4(9)1-2-5(8)10/h1-3H2

InChIKey

VRDGQQTWSGDXCU-UHFFFAOYSA-N

LogP

0.02859999999999996

Topological Polar Surface Area

63.68 Å²

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

224

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Sensitive to heat and humidity

Synonyms & References

English

AS-63595
BP-22653
FT-0604062
Iodoacetic acid N-hydroxysuccinimide ester, powder
2,5-Dioxopyrrolidin-1-yl 2-iodoacetate
1-[(Iodoacetyl)oxy]pyrrolidine-2,5-dione
PD171631
(2,5-dioxopyrrolidin-1-yl) 2-iodoacetate
Iodoacetic acid N-hydroxysuccinimide ester
N-(Iodoacetoxy)succinimide
MFCD00058451
Iodoacetic Acid N-Succinimidyl Ester
CS-W012257
Succinimidyl iodoacetate
DTXSID40391202
39028-27-8
N-Hydroxysuccinimidyl Iodoacetate
2-Iodoacetate N-Succinimidyl Ester
AKOS022185049
N-Succinimidyl Iodoacetate
HY-W011541
SY041743
N-SuccinimidylIodoacetate
S0844
iodoacetic acid, succinimidyl ester
H10193
C6H6INO4
(SIA);Succinimidyl iodoacetate
N-Iodoacetoxysuccinimide
SCHEMBL43673
VRDGQQTWSGDXCU-UHFFFAOYSA-N

MDL Number

MFCD00058451

Customs Code

2925190090

FAQ

What is 1-(2-Iodoacetoxy)-2,5-pyrrolidinedione (CAS: 39028-27-8)?

1-(2-Iodoacetoxy)-2,5-pyrrolidinedione (CAS: 39028-27-8) is a chemical compound with the molecular formula C6H9INO3O2. It is a yellow solid with a boiling point of 302°C. This compound is used in research and pharmaceutical applications for its specific reactivity and functional group properties.

What are the main uses of 1-(2-Iodoacetoxy)-2,5-pyrrolidinedione (CAS: 39028-27-8)?

1-(2-Iodoacetoxy)-2,5-pyrrolidinedione (CAS: 39028-27-8) is primarily used in research and pharmaceutical applications. It serves as a reagent for synthetic chemistry, particularly in the activation of carboxylic acids and esters. It is also used in organic synthesis to introduce iodine-containing functionalities.

Is 1-(2-Iodoacetoxy)-2,5-pyrrolidinedione (CAS: 39028-27-8) safe?

1-(2-Iodoacetoxy)-2,5-pyrrolidinedione (CAS: 39028-27-8) requires caution due to its reactivity and potential for generating strong iodine-containing species. It is essential to handle this compound with appropriate personal protective equipment and in a well-ventilated area. Storage and use should comply with local safety regulations and guidelines.

How should 1-(2-Iodoacetoxy)-2,5-pyrrolidinedione (CAS: 39028-27-8) be stored?

1-(2-Iodoacetoxy)-2,5-pyrrolidinedione (CAS: 39028-27-8) should be stored in a cool, dry, and well-ventilated area. It should be kept away from heat, moisture, and light. The compound should be stored in a suitable, tightly sealed container to prevent exposure to air and moisture. It is recommended to use a secondary containment system to prevent spills and ensure safety.