5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide | CAS No. 38234-21-8

5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide

Basic Information

CAS Number

38234-21-8

Molecular Formula

C55H76N16O12

Molecular Weight

1153.31 g/mol

AD

Basic Physical Properties

CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6

InChI

InChI=1S/C55H76N16O12/c1-4-59-53(82)44-12-8-20-71(44)54(83)38(11-7-19-60-55(56)57)66-49(78)39(21-30(2)3)65-46(75)27-62-47(76)40(22-31-13-15-34(73)16-14-31)67-52(81)43(28-72)70-50(79)41(23-32-25-61-36-10-6-5-9-35(32)36)68-51(80)42(24-33-26-58-29-63-33)69-48(77)37-17-18-45(74)64-37/h5-6,9-10,13-16,25-26,29-30,37-44,61,72-73H,4,7-8,11-12,17-24,27-28H2,1-3H3,(H,58,63)(H,59,82)(H,62,76)(H,64,74)(H,65,75)(H,66,78)(H,67,81)(H,68,80)(H,69,77)(H,70,79)(H4,56,57,60)/t37-,38-,39-,40-,41-,42-,43-,44-/m0/s1

InChIKey

DGCPIBPDYFLAAX-YTAGXALCSA-N

LogP

-2.6431300000000126

Topological Polar Surface Area

429.03999999999985 Ų

Hydrogen Bond Donor/Acceptor

17 / 28

Complexity

2280

Synonyms & References

English

  • F85427
  • Fertirelina
  • AC-8920
  • D07957
  • Fertirelin
  • Fertireline
  • Fertireline [INN-French]
  • 1-9-Luteinizing hormone-releasing factor (swine),9-(N-ethyl-L-prolinamide)-
  • 38234-21-8
  • CHEBI:177856
  • Fertirelinum
  • NCGC00262930-01
  • AKOS015896030
  • Fertirelinum [INN-Latin]
  • Fertirelin [INN:BAN]
  • Fertirelina [INN-Spanish]
  • TAP 031
  • CAS-38234-21-8
  • Fertirelin (INN)
  • Fertirelin acetate
  • CHEMBL3272563
  • DTXSID8057728
  • Q27286835
  • Tox21_113925
  • A824075
  • DTXCID9031517
  • UNII-Q041AO6T91
  • GTPL9341
  • Q041AO6T91
  • TAP-031
  • NS00120978

MDL Number

MFCD00133495

FAQ

What are the physical and chemical properties of 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide (CAS: 38234-21-8)?

The compound is a peptide with a molecular weight of approximately 1388.81 g/mol. It is soluble in water and slightly soluble in ethanol. It exhibits moderate reactivity, particularly with nucleophiles and reducing agents. The crystalline form is stable under acidic and neutral conditions but may decompose under basic conditions.

How is 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide (CAS: 38234-21-8) typically synthesized?

The compound is synthesized through multi-step peptide coupling reactions, typically using Fmoc chemistry. Commonly, the synthesis involves a series of solid-phase peptide synthesis steps followed by cleavage from the solid support and purification. Yields are generally around 75-85% with high structural selectivity.

What industries use 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide (CAS: 38234-21-8)?

This compound is primarily used in pharmaceuticals for its potential as a bioactive molecule. It is also of interest in the development of new materials and sensors due to its unique chemical structure. Some researchers explore its use in semiconductors for specific applications requiring precise molecular architecture.

What precautions should be taken when handling 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide (CAS: 38234-21-8)?

When handling this compound, wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to avoid inhalation. In case of a spill, use appropriate absorbents and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.

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