1,2-Ethanediyl bis(bromoacetate)

Basic Information

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CAS Number

3785-34-0

Molecular Formula

C6H8Br2O4

Molecular Weight

303.93 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

178°C (rough estimate)

Refractive Index

1.4840 (estimate)

SMILES

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C(COC(=O)CBr)OC(=O)CBr

InChI

InChI=1S/C6H8Br2O4/c7-3-5(9)11-1-2-12-6(10)4-8/h1-4H2

InChIKey

WGHAPLWNJPAJDE-UHFFFAOYSA-N

LogP

0.8625999999999999

Topological Polar Surface Area

52.6 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

142

Synonyms & References

English

1,2-Ethanediyl bromoacetate
Acetic acid, bromo-, ethylene ester
W-106507
3785-34-0
NSC-406054
NSC25854
Bromoacetic acid 1,2-ethanediyl ester
Ethylene glycol, bis(bromoacetate)
SCHEMBL1434603
Bromoacetic acid, ethylene ester
Bromoacetic acid ethylene ester
DTXSID20191282
Ethane-1,2-diylbis(2-bromoacetate)
D97238
AKOS015964337
NSC 25854
WLN: E1VO2OV1E
1-02-00-00097 (Beilstein Handbook Reference)
AS-75620
AI3-18935
NSC406054
Pandurol
Acetic acid, bromo-, 1,2-ethanediyl ester
NSC 406054
NSC-25854
1,2-BIS(MONOBROMOACETOXY)ETHANE
Ethane-1,2-diyl bis(2-bromoacetate)
BRN 1782335
Q27270866
1,2-Bis(bromoacetoxy)ethane
EINECS 223-250-4

MDL Number

MFCD00466788

Customs Code

2915900090

FAQ

What are the physical and chemical properties of 1,2-Ethanediyl bis(bromoacetate) (CAS: 3785-34-0)?

1,2-Ethanediyl bis(bromoacetate) (CAS: 3785-34-0) is a crystalline compound with a molecular weight of approximately 234.03 g/mol. It is slightly soluble in water and organic solvents. The compound is highly reactive, particularly towards nucleophiles, making it useful in a variety of synthetic applications. It has a melting point of around 56-58°C and is stable under normal conditions but requires proper handling due to its reactivity.

How is 1,2-Ethanediyl bis(bromoacetate) (CAS: 3785-34-0) typically synthesized?

1,2-Ethanediyl bis(bromoacetate) (CAS: 3785-34-0) is typically synthesized through the reaction of ethylene glycol with bromoacetyl bromide in the presence of a base such as sodium hydroxide. The reaction proceeds under basic conditions to form the bis(bromoacetate) product. The process involves careful control of reaction temperature and pH to ensure high yield and selectivity. Commonly, the yield of the reaction is around 85-90%, with the product requiring purification by recrystallization.

What industries use 1,2-Ethanediyl bis(bromoacetate) (CAS: 3785-34-0)?

1,2-Ethanediyl bis(bromoacetate) (CAS: 3785-34-0) is used in various industries, particularly in the pharmaceutical sector for the synthesis of certain drugs and intermediates. It is also utilized in the polymer industry as a cross-linking agent, in semiconductor manufacturing for etching processes, and in the production of various sensors due to its reactivity and stability under specific conditions.

What precautions should be taken when handling 1,2-Ethanediyl bis(bromoacetate) (CAS: 3785-34-0)?

When handling 1,2-Ethanediyl bis(bromoacetate) (CAS: 3785-34-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat to prevent direct contact with the skin and eyes. The substance should be handled in a well-ventilated area or fume hood. In case of a spill, it should be contained and disposed of following standard chemical waste procedures. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.