N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide | CAS No. 3778-73-2

N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

Basic Information

CAS Number

3778-73-2

Molecular Formula

C7H15Cl2N2O2P

Molecular Weight

261.09 g/mol

AD

Basic Physical Properties

Melting Point

48 ºC

Boiling Point

336.1°C at 760 mmHg

Density

1.33

Flash Point

157.1 °C

C1CN(P(=O)(OC1)NCCCl)CCCl

InChI

InChI=1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)

InChIKey

HOMGKSMUEGBAAB-UHFFFAOYSA-N

LogP

1.884

Topological Polar Surface Area

41.57 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

218

Safety Information

View Safety Information

GHS Hazard Pictograms

H301H301
H319H319

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral
H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 6.1 Class 6.1

Toxicity

LD50 in rats (mg/kg): 160 i.p. (Arnold, 1973); also reported as 150 i.p. (Brock)

Synonyms & References

English

  • NCGC00016639-01
  • IFOSFAMIDE [VANDF]
  • N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]
  • Ifosfamide, analytical reference material
  • NCGC00259364-01
  • 3-(2-chloroethyl)-2-((2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide
  • ISOPHOSPHAMIDE [IARC]
  • SR-05000002022
  • NCGC00179435-07
  • Ifosfamidum (INN-Latin)
  • N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid
  • IFEX (TN)
  • 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide
  • Ifosfamide in bulk
  • 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1,3,2$l^{5}-oxazaphosphinan-2-one
  • N-(2-CHLORAETHYL)-N'-(2 CHLOROETHYL)-N'-o-PROPYLEN-PHOSPHORSAEUREESTER-DIAMID
  • N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide
  • FT-0670282
  • 2,3-(N,N(,)-BIS(2-CHLOROETHYL)DIAMIDO)-1,3,2-OXAZAPHOSPHORIDINOXY
  • Ifosphamide
  • NCGC00179435-01
  • Ifosfamide, European Pharmacopoeia (EP) Reference Standard
  • 3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide
  • IFOSFAMIDE [USP-RS]
  • Pharmakon1600-01505480
  • Isofosfamide
  • Mitoxana
  • CHEBI:5864
  • SW197177-4
  • Z-4942
  • Ifosfamidum [INN-Latin]

MDL Number

MFCD00057374

Customs Code

2934999090

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