N-Acetylcytidine

Basic Information

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CAS Number

3768-18-1

Molecular Formula

C11H15N3O6

Molecular Weight

285.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

199 ºC (dec.)

SMILES

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CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O

InChI

InChI=1S/C11H15N3O6/c1-5(16)12-7-2-3-14(11(19)13-7)10-9(18)8(17)6(4-15)20-10/h2-3,6,8-10,15,17-18H,4H2,1H3,(H,12,13,16,19)/t6-,8-,9-,10-/m1/s1

InChIKey

NIDVTARKFBZMOT-PEBGCTIMSA-N

LogP

-2.1867999999999994

Topological Polar Surface Area

133.91 Å²

Hydrogen Bond Donor/Acceptor

4 / 9

Complexity

477

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Acetamide, N-(1,2-dihydro-2-oxo-1-beta-D-ribofuranosyl-4-pyrimidinyl)
3768-18-1
n4-Acetylcytidine;n-acetylcytidine
BP-58622
N-{1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}acetamide
N-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
4-[(1-Hydroxyethylidene)amino]-1-pentofuranosylpyrimidin-2(1H)-one
N-[1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-oxo-pyrimidin-4-yl]acetamide;N4-Acetylcytidine
4-N-acetyl-cytidine
CS-0030784
N4-Acetylcytidine, >=98%
N-{1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}acetamide
EINECS 223-195-6
N4 -Acetylcytidine
F12709
SCHEMBL453447
4-Acetyl-1-(beta-delta-ribofuranosyl)cytosine
Cytidine, N-acetyl-
4-Acetyl-1-(beta-D-ribofuranosyl)cytosine
C22293
N4-Acetyl-D-cytidine
NIDVTARKFBZMOT-PEBGCTIMSA-N
DTXSID40958718
n-acetyl-Cytidine
AKOS015896940
AC-32170
N-Acetylcytidine
Q20890503
4-Acetylcytidine; N4-Acetylcytidine
HY-W019670
n(4)-acetylcytidine

MDL Number

MFCD00006540

Customs Code

2934999090

FAQ

What are the physical and chemical properties of N-Acetylcytidine (CAS: 3768-18-1)?

N-Acetylcytidine (CAS: 3768-18-1) is a white to off-white crystalline powder. Its molecular weight is approximately 267.21 g/mol. It is slightly soluble in water and ethanol. Chemically, it is stable under normal conditions but can react with strong acids or bases. It is used in research primarily for its structural properties and as a precursor in some synthetic pathways.

How is N-Acetylcytidine (CAS: 3768-18-1) typically synthesized?

N-Acetylcytidine (CAS: 3768-18-1) is typically synthesized via acetylation of cytidine using acetic anhydride in the presence of a catalyst such as pyridine. The reaction is carried out under mild conditions, and the yield is generally around 70-80%. Selectivity and purity can be improved by maintaining appropriate reaction parameters.

What industries use N-Acetylcytidine (CAS: 3768-18-1)?

N-Acetylcytidine (CAS: 3768-18-1) is primarily used in the pharmaceutical industry for its structural properties and as an intermediary in organic synthesis. It is also relevant in the research and development of nucleoside analogs for potential drug applications.

What precautions should be taken when handling N-Acetylcytidine (CAS: 3768-18-1)?

When handling N-Acetylcytidine (CAS: 3768-18-1), wear appropriate personal protective equipment (PPE) such as gloves and a lab coat. Store it in a cool, dry place away from direct sunlight. Use a fume hood during synthesis and manipulation to minimize inhalation risk. In case of spill, clean up with appropriate absorbents and follow laboratory safety guidelines. Refer to the Safety Data Sheet (SDS) for more detailed information.