(6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Basic Information

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CAS Number

36923-17-8

Molecular Formula

C7H8N2O3S

Molecular Weight

200.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

227-232°C

Boiling Point

536.902°C at 760 mmHg

Density

1.699

Flash Point

278.508°C

Refractive Index

1.735

SMILES

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C1C=C(N2C(S1)C(C2=O)N)C(=O)O

InChI

InChI=1S/C7H8N2O3S/c8-4-5(10)9-3(7(11)12)1-2-13-6(4)9/h1,4,6H,2,8H2,(H,11,12)/t4-,6-/m1/s1

InChIKey

RJFPBECTFIUTHB-INEUFUBQSA-N

LogP

-0.8027000000000004

Topological Polar Surface Area

83.63 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

315

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

7-ANCA
DTXSID30471320
C74904
SCHEMBL9516059
AKOS016005587
7-Amino-3-cephem-4-carboxylicacid
MFCD08063340
AS-12320
RJFPBECTFIUTHB-INEUFUBQSA-N
7beta-Amino-ceph-3-em-4-carboxylic acid
(6r,7r)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic
7beta-amino-3-cephem-4-carboxylic acid
36923-17-8
7-Amino-3-cephem-4-carboxylic acid
CS-0157770
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-8-oxo-,(6R,7R)-
(6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-Amino-3-nor-3-cephem-4-carboxylic acid
BCP10737
7-Amino-3-norcephalosporanic acid
7-Amino-3-cephem-4-carboxylic Acid
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-8-oxo-, (6R,7R)-
FCH3989615
ST24034952
923A178
(6r,7r)-7-amino-8-oxo-
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

MDL Number

MFCD08063340

Customs Code

2941905990

FAQ

What is (6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (CAS: 36923-17-8)?

(6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, also known as Aztreonam, is a monobactam antibiotic with a unique chemical structure. It is a bicyclic beta-lactam antibiotic used primarily for treating infections caused by Gram-negative bacteria.

What are the main uses of (6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (CAS: 36923-17-8)?

(6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, or Aztreonam, is primarily used in the treatment of infections caused by Gram-negative bacteria. It is administered intravenously and is effective against a variety of such bacteria, making it a valuable tool in clinical settings.

Is (6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (CAS: 36923-17-8) safe?

(6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, or Aztreonam, is generally safe when used as directed by a healthcare provider. However, like any medication, it can cause side effects such as allergic reactions and gastrointestinal issues. Proper storage and handling are crucial to ensure safety.

How should (6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (CAS: 36923-17-8) be stored?

(6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, or Aztreonam, should be stored at a temperature between 15°C and 30°C (59°F and 86°F) in a tightly closed container to protect it from light and moisture. Avoid storing it near heat sources or direct sunlight to maintain its efficacy and safety.