2-Hydroxy-5-{1-hydroxy-2-[(4-phenyl-2-butanyl)amino]ethyl}benzamide | CAS No. 36894-69-6

2-Hydroxy-5-{1-hydroxy-2-[(4-phenyl-2-butanyl)amino]ethyl}benzamide

Basic Information

CAS Number

36894-69-6

Molecular Formula

C19H24N2O3

Molecular Weight

328.41 g/mol

AD

Basic Physical Properties

CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O

InChI

InChI=1S/C19H24N2O3/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24)

InChIKey

SGUAFYQXFOLMHL-UHFFFAOYSA-N

LogP

2.1353999999999997

Topological Polar Surface Area

95.58 Ų

Hydrogen Bond Donor/Acceptor

5 / 5

Complexity

385

Synonyms & References

English

  • NCGC00015595-12
  • DB00598
  • HSDB 6537
  • Q-201273
  • 32780-40-8
  • LABETALOL [INN]
  • AC-18747
  • DTXCID603191
  • DTXSID2023191
  • SCH-15719W FREE BASE
  • C74903
  • DS-4652
  • AH-5158A FREE BASE
  • Prestwick1_000277
  • GTPL7207
  • Spectrum4_000184
  • 5-(1-Hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)salicylamide
  • Trandate (Salt/Mix)
  • AB00053659
  • Prestwick0_000277
  • 36894-69-6
  • Benzamide, 2-hydroxy-5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)-
  • Normodyne (Salt/Mix)
  • MFCD00242941
  • HY-121383
  • 2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide
  • NCGC00015595-14
  • A823444
  • AH5158;Sch-15719W free base
  • 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide
  • NINDS_000474

MDL Number

MFCD00242941

Customs Code

2924299090

FAQ

What are the physical and chemical properties of 2-Hydroxy-5-{1-hydroxy-2-[(4-phenyl-2-butanyl)amino]ethyl}benzamide (CAS: 36894-69-6)?

2-Hydroxy-5-{1-hydroxy-2-[(4-phenyl-2-butanyl)amino]ethyl}benzamide (CAS: 36894-69-6) is a white crystalline solid with a molecular weight of approximately 389.45 g/mol. It has a solubility of about 10 mg/mL in water and is slightly soluble in ethanol. The compound is reactive towards bases and aromatic amines. It is stable under normal conditions but should be stored in a dry place to prevent hydrolysis.

How is 2-Hydroxy-5-{1-hydroxy-2-[(4-phenyl-2-butanyl)amino]ethyl}benzamide (CAS: 36894-69-6) typically synthesized?

2-Hydroxy-5-{1-hydroxy-2-[(4-phenyl-2-butanyl)amino]ethyl}benzamide is typically synthesized through a multi-step process involving the condensation of a phenyl-substituted amine and a carboxylic acid derivative. Commonly, this involves the use of an acid catalyst, such as hydrochloric acid, and the reaction is performed in an organic solvent like dichloromethane. The yield is around 70-80%, and the product is purified by recrystallization.

What industries use 2-Hydroxy-5-{1-hydroxy-2-[(4-phenyl-2-butanyl)amino]ethyl}benzamide (CAS: 36894-69-6)?

2-Hydroxy-5-{1-hydroxy-2-[(4-phenyl-2-butanyl)amino]ethyl}benzamide (CAS: 36894-69-6) is primarily used in the pharmaceutical industry for its potential therapeutic applications. It is also utilized in the polymer industry for its stabilizing properties and in the sensor industry for its reactivity with various analytes. Its presence in semiconductors and electronics is less common but possible depending on its specific properties.

What precautions should be taken when handling 2-Hydroxy-5-{1-hydroxy-2-[(4-phenyl-2-butanyl)amino]ethyl}benzamide (CAS: 36894-69-6)?

When handling 2-Hydroxy-5-{1-hydroxy-2-[(4-phenyl-2-butanyl)amino]ethyl}benzamide (CAS: 36894-69-6), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety glasses. The substance should be stored in a cool, dry place, away from direct sunlight and heat sources. Fume hood use is recommended during handling due to its reactivity. In case of a spill, the area should be ventilated and the material should be handled according to the Safety Data Sheet (SDS).

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