5-Amino-1H-isoindole-1,3(2H)-dione

Basic Information

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CAS Number

3676-85-5

Molecular Formula

C8H6N2O2

Molecular Weight

162.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

290 ºC

Boiling Point

288.82°C (rough estimate)

Refractive Index

1.5770 (estimate)

SMILES

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C1=CC2=C(C=C1N)C(=O)NC2=O

InChI

InChI=1S/C8H6N2O2/c9-4-1-2-5-6(3-4)8(12)10-7(5)11/h1-3H,9H2,(H,10,11,12)

InChIKey

PXRKCOCTEMYUEG-UHFFFAOYSA-N

LogP

0.1524000000000002

Topological Polar Surface Area

72.19 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

239

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Isoindole, 1,3(2H)-dione, 5-amino-
BP-11004
FT-0617602
SY048742
Citricacid
5-Aminoisoindoline-1,3-dione
MFCD00041854
EN300-02536
BDBM625947
NS00030088
SR-01000524005-1
DTXSID8063127
A823362
5-Aminophthalimide
1H-Isoindole-1,3(2H)-dione, 5-amino-
AMY22085
SR-01000524005
5-Amino-2,3-Dihydro-1H-Isoindole-1,3-Dione
F0907-4240
NSC 25173
1H-Isoindole-1, 5-amino-
A0966
W-106588
CS-0028341
AC-30018
4-Aminophthalimide
5-Amino-1H-isoindole-1,3(2H)-dione #
BCP18648
Oprea1_375068
SCHEMBL372282
NSC25173

MDL Number

MFCD00041854

Customs Code

2925190090

FAQ

What are the physical and chemical properties of 5-Amino-1H-isoindole-1,3(2H)-dione (CAS: 3676-85-5)?

5-Amino-1H-isoindole-1,3(2H)-dione (CAS: 3676-85-5) is a white crystalline solid with a molecular weight of approximately 192.18 g/mol. It has a solubility of about 0.15 g/100 mL in water at 25°C. Chemically, it reacts readily with acids and bases, making it useful in various chemical transformations. It is also stable under normal conditions, but care should be taken to avoid strong oxidizing agents.

How is 5-Amino-1H-isoindole-1,3(2H)-dione (CAS: 3676-85-5) typically synthesized?

5-Amino-1H-isoindole-1,3(2H)-dione (CAS: 3676-85-5) is typically synthesized by the condensation of 1H-isoindole-1,3(2H)-dione with an amine. This reaction can be carried out using various amine reagents under basic conditions, with good yield and selectivity. Common catalysts include sodium hydride and potassium hydroxide.

What industries use 5-Amino-1H-isoindole-1,3(2H)-dione (CAS: 3676-85-5)?

5-Amino-1H-isoindole-1,3(2H)-dione (CAS: 3676-85-5) is widely used in the pharmaceutical industry for the synthesis of nitrogen heterocyclic compounds. It is also utilized in the polymer industry for the production of certain polymers with unique properties. Additionally, it finds applications in the sensor and semiconductor industries due to its aromatic structure and reactivity.

What precautions should be taken when handling 5-Amino-1H-isoindole-1,3(2H)-dione (CAS: 3676-85-5)?

When handling 5-Amino-1H-isoindole-1,3(2H)-dione (CAS: 3676-85-5), it is important to wear appropriate personal protective equipment (PPE), such as gloves and safety goggles. Work should be carried out in a fume hood to minimize exposure to vapors. Spills should be cleaned up using appropriate absorbent materials and by following the safety data sheet (SDS) recommendations. Ensure proper ventilation and avoid contact with eyes, skin, and inhalation of dust or vapors.