2,2-Difluoroacetamide

Basic Information

View in Editor

CAS Number

359-38-6

Molecular Formula

C2H3F2NO

Molecular Weight

95.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

SMILES

View in Editor

C(C(=O)N)(F)F

InChI

InChI=1S/C2H3F2NO/c3-1(4)2(5)6/h1H,(H2,5,6)

InChIKey

ZMIBIIAWFMCVFD-UHFFFAOYSA-N

LogP

-0.2631999999999998

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

62.6

Safety Information

View Safety Information

Hazard Statement

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Difluoroacetamide
DTXSID40382034
YMJDMVZTQVWJJQ-UHFFFAOYSA-N
FT-0676809
CHEMBL156852
359-38-6
CS-0109914
SB85512
2,2-Difluoro-acetamide
SY162673
C2H3F2NO
EN300-181159
2,2-difluoroacetamide
MFCD01896431
3-carboxy-5-nitrobenzoic acid
A874496
D76959
AKOS003269748
Z33546481
BDBM50226188
ZMIBIIAWFMCVFD-UHFFFAOYSA-N
Acetamide, 2,2-difluoro-
2,2-Difluoroacetamide
Acetamide,2,2-difluoro-

MDL Number

MFCD01896431

Customs Code

2924199090

FAQ

What regulatory guidelines apply to 2,2-Difluoroacetamide (CAS: 359-38-6)?

2,2-Difluoroacetamide (CAS: 359-38-6) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a skin and eye irritant. In Europe, it is also subject to the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) regulation. The Food and Drug Administration (FDA) may require reporting under the Toxic Substances Control Act (TSCA) for certain uses. The Environmental Protection Agency (EPA) oversees its use in the United States, particularly concerning environmental releases and disposal.

Are there alternatives to 2,2-Difluoroacetamide (CAS: 359-38-6) in synthesis?

Several alternatives to 2,2-Difluoroacetamide (CAS: 359-38-6) exist, including 2,2-Dichloroacetamide and 2,2-Dibromoacetamide, which can be used as precursors in similar reactions. Other strategies include the use of fluorinated acetic acids or amides, which can offer similar functionality with different handling characteristics.

What is the market or research trend for 2,2-Difluoroacetamide (CAS: 359-38-6)?

The market for 2,2-Difluoroacetamide (CAS: 359-38-6) is driven by its use in the synthesis of fluorinated compounds, particularly in pharmaceuticals and agrochemicals. Research trends are focusing on its use as a key intermediate in developing new drugs and crop protection agents. Recent studies are also exploring its role in the preparation of bioactive molecules, with an increasing emphasis on sustainable and eco-friendly synthesis methods.

How should waste containing 2,2-Difluoroacetamide (CAS: 359-38-6) be handled?

Waste containing 2,2-Difluoroacetamide (CAS: 359-38-6) should be collected in appropriate containers and labeled as hazardous. Disposal should follow local, national, and international regulations, typically involving incineration or professional chemical waste disposal services. Environmental protection measures include ensuring no spillage occurs during handling and that waste is neutralized before disposal to minimize environmental impact.