1-Methyl-1H-imidazole hydrochloride (1:1)

Basic Information

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CAS Number

35487-17-3

Molecular Formula

C4H7ClN2

Molecular Weight

118.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

231.7°C at 760 mmHg

SMILES

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CN1C=CN=C1.Cl

InChI

InChI=1S/C4H6N2.ClH/c1-6-3-2-5-4-6;/h2-4H,1H3;1H

InChIKey

STCBHSHARMAIOM-UHFFFAOYSA-N

LogP

0.8418999999999999

Topological Polar Surface Area

17.82 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

44.8

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1-methyl-1H-imidazole hydrochloride
1-methylimidazole;hydrochloride
1-Methylimidazolium Chloride Quality
1-Methylimidazolium chloride
35487-17-3
DTXSID60479995
1-Methylimidazolium chloride, 95%
1-Methylimidazole hydrochloride
AS-79001
n-methylimidazolium chloride
AKOS015912541
CS-0188308
n-methylimidazole hydrochloride
1H-Imidazole,1-methyl-, hydrochloride (1:1)
1-methylimidazole,hydrochloride
1-METHYLIMIDAZOLIUM CHLORIDE
Basionic(TM) AC 75
BASIONIC AC 75
NMI hydrochloride
Basionics® AC 75

MDL Number

MFCD06798176

Customs Code

2933290090

FAQ

What are the physical and chemical properties of 1-Methyl-1H-imidazole hydrochloride (CAS: 35487-17-3)?

1-Methyl-1H-imidazole hydrochloride (CAS: 35487-17-3) is a crystalline solid with a molecular weight of approximately 120.6 g/mol. It has a high solubility in water and ethanol. This compound is moderately reactive, showing basic properties due to the imidazole ring and hydrochloride functionality. It is stable under normal conditions but should be stored in a dry environment to prevent hydrolysis.

How is 1-Methyl-1H-imidazole hydrochloride (CAS: 35487-17-3) typically synthesized?

1-Methyl-1H-imidazole hydrochloride is typically synthesized by reacting 1-methylimidazole with hydrochloric acid. The reaction is conducted in a polar aprotic solvent such as dimethylformamide (DMF) at room temperature. The yield is around 85-90%, and the product is isolated by filtration and drying. This method provides a high level of purity and selectivity.

What industries use 1-Methyl-1H-imidazole hydrochloride (CAS: 35487-17-3)?

1-Methyl-1H-imidazole hydrochloride (CAS: 35487-17-3) finds applications in various industries. It is used in the pharmaceutical industry as a precursor for drug synthesis, in the polymer industry as an additive for improving material properties, and in the semiconductor industry for etching processes. Additionally, it is utilized in the sensing applications for detecting specific gases and in analytical chemistry for reagents.

What precautions should be taken when handling 1-Methyl-1H-imidazole hydrochloride (CAS: 35487-17-3)?

When handling 1-Methyl-1H-imidazole hydrochloride (CAS: 35487-17-3), safety should be a top priority. Always wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work in a well-ventilated area or fume hood to avoid inhalation of fumes. Ensure proper storage in a cool, dry place away from direct sunlight. In the event of a spill, neutralize with a base and dispose of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed handling and disposal information.