N-Acetyl-L-glutamine

Basic Information

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CAS Number

35305-74-9

Molecular Formula

C7H12N2O4

Molecular Weight

188.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

206-208 ºC

Boiling Point

604.9 °C at 760 mmHg

Density

1.29

Flash Point

319.6 °C

Specific Rotation

-12.4 º (c=2.5% in H2O)

SMILES

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CC(=O)NC(=O)CCC(C(=O)O)N

InChI

InChI=1S/C7H12N2O4/c1-4(10)9-6(11)3-2-5(8)7(12)13/h5H,2-3,8H2,1H3,(H,12,13)(H,9,10,11)/t5-/m0/s1

InChIKey

SGKPDOQKJBOJTE-YFKPBYRVSA-N

LogP

-1.1587999999999998

Topological Polar Surface Area

109.48999999999998 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

227

Synonyms & References

English

(2S)-5-acetamido-2-amino-5-oxopentanoic acid
DTXSID40956739
A822723
(S)-5-Acetamido-2-amino-5-oxopentanoicacid
FD20068
(S)-5-Acetamido-2-amino-5-oxopentanoic acid
(S)-5-Acetamido-2-amino-5-oxopentanoic acid, 95% (Ac-L-Gln-OH)
AKOS015950979
BS-16651
MFCD20926246
SCHEMBL2909135
35305-74-9
CS-0153997
(S)-2-Acetamido-5-amino-5-oxopentanoic acid
Ac-Gln-OH
N-ACETYL-L-GLUTAMINE
ACMC-20m2m1
CTK3G7660
Ethanimidic acid, N-acetyl-, ethyl ester
Ethyl N-acetylacetimidate
N-acetyl ethyl acetimidate
N-acetyl glutamine
N-Acetylacetimidsaeure-ethylester
Aceglutamide
L-Glutamine, N-acetyl-
Nalpha-Acetyl-L-glutamine
N-alpha-Acetyl-L-glutamine
L-Glutamine, N2-acetyl-
N-Acetylglutamine
N2-acetylglutamine
Aceglutamide [INN]

MDL Number

MFCD00038159

FAQ

What are the physical and chemical properties of N-Acetyl-L-glutamine (CAS: 35305-74-9)?

N-Acetyl-L-glutamine (CAS: 35305-74-9) is a white crystalline powder with a molecular weight of approximately 203.23 g/mol. It is soluble in water and has good stability under neutral conditions. However, it is susceptible to hydrolysis in acidic or strongly basic environments.

How is N-Acetyl-L-glutamine (CAS: 35305-74-9) typically synthesized?

N-Acetyl-L-glutamine is typically synthesized through the acetylation of L-glutamine. This process involves the reaction of L-glutamine with acetic anhydride in the presence of a strong acid catalyst, such as sulfuric acid, leading to high yield and selectivity. The reaction is carried out under mild conditions to ensure product purity.

What industries use N-Acetyl-L-glutamine (CAS: 35305-74-9)?

N-Acetyl-L-glutamine (CAS: 35305-74-9) is widely used in the pharmaceutical industry as a precursor for drug development. It also finds applications in the food industry as a food additive and in the cosmetic industry as a skin care ingredient. Additionally, it is used in research and development for its biological activity.

What precautions should be taken when handling N-Acetyl-L-glutamine (CAS: 35305-74-9)?

When handling N-Acetyl-L-glutamine (CAS: 35305-74-9), it is important to wear appropriate personal protective equipment (PPE), such as gloves and safety goggles. Store the compound in a cool, dry place away from direct sunlight and flammable materials. In case of spillage, use a fume hood and appropriate spill cleanup materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and follow all laboratory safety guidelines.