2-Amino-2-(2-chlorophenyl)cyclohexanone

Basic Information

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CAS Number

35211-10-0

Molecular Formula

C12H14ClNO

Molecular Weight

223.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

368.6°Cat760mmHg

Density

1.208

Flash Point

176.7°C

Refractive Index

1.568

SMILES

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C1CCC(C(=O)C1)(C2=CC=CC=C2Cl)N

InChI

InChI=1S/C12H14ClNO/c13-10-6-2-1-5-9(10)12(14)8-4-3-7-11(12)15/h1-2,5-6H,3-4,7-8,14H2

InChIKey

BEQZHFIKTBVCAU-UHFFFAOYSA-N

LogP

2.637100000000001

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

256

Synonyms & References

English

UNII-XQY6JVF94X
CHEMBL1039
N-desmethylketamine
norketamine
2-Amino-2-(o-chlorophenyl)cyclohexanone
NS00000045
35211-10-0
(+/-)-Norketamine
NCGC00159535-01
2-Amino-2-(o-chlorophenyl) cyclohexanone
J397.916D
2-(o-Chlorophenyl)-2-aminocyclohexanone
Cyclohexanone, 2-amino-2-(2-chlorophenyl)-
Ketamine-M nor
SCHEMBL3390132
DTXSID40891434
W12824
XQY6JVF94X
2-amino-2-(2-chlorophenyl)cyclohexan-1-one
BRD-A10355991-003-01-8
N-Demethylketamine
Q20164391
CHEBI:91519
Norketamine (1.0mg/ml in Methanol)
AKOS005215885
Cyclohexanone,2-amino-2-(2-chlorophenyl)-
Norketamine
(+/-)-Norketamine hydrochloride
NORKETAMINE HYDROCHLORIDE

MDL Number

MFCD03788616

Customs Code

2922399090

FAQ

What are the physical and chemical properties of 2-Amino-2-(2-chlorophenyl)cyclohexanone (CAS: 35211-10-0)?

2-Amino-2-(2-chlorophenyl)cyclohexanone (CAS: 35211-10-0) is a crystalline compound with a molecular weight of approximately 235.02 g/mol. It has a solubility of about 1 g/L in water and is sparingly soluble in organic solvents. This compound is moderately reactive towards nucleophiles and exhibits good stability under normal conditions. It is used as a key intermediate in the synthesis of various pharmaceuticals and materials.

How is 2-Amino-2-(2-chlorophenyl)cyclohexanone (CAS: 35211-10-0) typically synthesized?

2-Amino-2-(2-chlorophenyl)cyclohexanone (CAS: 35211-10-0) is typically synthesized via a multistep process involving the reaction of 2-chlorophenylcyclohexanone with an amine. The synthesis involves the use of a catalyst, such as a Lewis acid, to promote the nucleophilic substitution. The reaction is carried out under mild conditions, and the product is purified by recrystallization or other standard methods.

What industries use 2-Amino-2-(2-chlorophenyl)cyclohexanone (CAS: 35211-10-0)?

2-Amino-2-(2-chlorophenyl)cyclohexanone (CAS: 35211-10-0) is primarily used in the pharmaceutical industry as a key intermediate in the synthesis of drugs. It is also utilized in the polymer industry for the production of advanced materials and in the sensor industry due to its functional groups. Additionally, it has applications in the semiconductor industry for specific chemical processes.

What precautions should be taken when handling 2-Amino-2-(2-chlorophenyl)cyclohexanone (CAS: 35211-10-0)?

When handling 2-Amino-2-(2-chlorophenyl)cyclohexanone (CAS: 35211-10-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handle the compound in a well-ventilated environment or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials, and the area should be well ventilated. Refer to the safety data sheet (SDS) for detailed handling and emergency procedures.