Blasticidin S hydrochloride

Basic Information

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CAS Number

3513-03-9

Molecular Formula

C17H27ClN8O5

Molecular Weight

458.91 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

White

Melting Point

224-225 °C (decomp)

Boiling Point

772.1 °C at 760 mmHg

Water Solubility

Soluble in water. Insoluble in organic solvents.

Flash Point

No data available

Solubility

Soluble in Water (greater than 25 mg/ml)

Refractive Index

1.71

Vapor Pressure

No data available

SMILES

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CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl

InChI

InChI=1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29;/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29);1H/t9-,10-,13+,14-;/m0./s1

InChIKey

YQXYQOXRCNEATG-NMQKUDMSSA-N

LogP

-1.7969299999999957

Topological Polar Surface Area

215.67000000000002 Å²

Hydrogen Bond Donor/Acceptor

9 / 13

Complexity

795

Safety Information

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GHS Hazard Pictograms

H300

Hazard Statement

H300 Fatal if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Stability

Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.

Sensitiveness

Sensitive to moisture

Synonyms & References

English

(2S,3S,6R)-6-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-((S)-3-amino-5-(1-methylguanidino)pentanamido)-3,6-dihydro-2H-pyran-2-carboxylic acid hydrochloride
(2S,3S,6R)-3-[[(3S)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid;hydrochloride
(S)-4-[[3-Amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-?-D-erythro-hex-2-enopyranuronic acid hydrochloride
Blasticidin S (hydrochloride)
AKOS025147372
HY-103401
MFCD02091640
CS-0027828
Blasticidin S hydrochloride
blasticidin S HCl
Bla-S; Blasticidin S; Blasticidin S HCl
(2S,3S,6R)-6-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-[(3S)-3-amino-5-(N-methylcarbamimidamido)pentanamido]-3,6-dihydro-2H-pyran-2-carboxylic acid hydrochloride
3513-03-9
BlasticidinShydrochloride
BLASTICIDINE S HYDROCHLORIDE
BLASTICIDIN S HCL
BLASTICIDIN S HYDROCHLORIDE
BLASTICIDIN S, HYDROCHLORIDE, STREPTOMYCES GRISEOCHROMOGENES
Blasticidine S hydrochloride,Blasticidin S
(S)-4-[[3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-Hex-2-enopyranuronic acid,monohydrochloride
Blasticidine S HCl
Blasticidine S hydrochloride solution
b-D-erythro-Hex-2-enopyranuronicacid,4-[[3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-,monohydrochloride, (S)- (9CI)
b-D-erythro-Hex-2-enopyranuronicacid,4-[[3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl...
b-D-erythro-Hex-2-enopyranuronicacid,4-[[3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-
Blasticidin S HCl
Blasticidine S hydrochloride
Blasticidin-S - HCl
BlasticidinS,monohydrochloride (8CI)
B4879
CID 124080960

MDL Number

MFCD02091640

Customs Code

29349990

FAQ

What is Blasticidin S hydrochloride (CAS: 3513-03-9)?

Blasticidin S hydrochloride (CAS: 3513-03-9) is an antibiotic that inhibits protein synthesis by binding to the peptidyl transferase center of ribosomes. It is a macrocyclic peptide with a molecular weight of approximately 1862.68 Da.

What are the main uses of Blasticidin S hydrochloride (CAS: 3513-03-9)?

Blasticidin S hydrochloride is primarily used in molecular biology as a selectable marker for stable transfection of cells. It is also used in animal feed to prevent fungal infection and in research for gene expression studies.

Is Blasticidin S hydrochloride (CAS: 3513-03-9) safe?

Blasticidin S hydrochloride (CAS: 3513-03-9) is generally considered safe when used as directed. However, it should be handled with care due to its potential toxicity. Proper protective measures, such as gloves and goggles, should be worn during handling.

How should Blasticidin S hydrochloride (CAS: 3513-03-9) be stored?

Blasticidin S hydrochloride (CAS: 3513-03-9) should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container to maintain its potency and stability.