4-(trifluoromethyl)-1,3-thiazol-2-amine

Basic Information

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CAS Number

349-49-5

Molecular Formula

C4H3F3N2S

Molecular Weight

168.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

60-62°C

Boiling Point

214°C at 760 mmHg

Flash Point

83.2℃

SMILES

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C1=C(N=C(S1)N)C(F)(F)F

InChI

InChI=1S/C4H3F3N2S/c5-4(6,7)2-1-10-3(8)9-2/h1H,(H2,8,9)

InChIKey

OVMGTNMCYLZGLS-UHFFFAOYSA-N

LogP

1.7441

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

126

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

FS-1246
AKOS000123903
4-(trifluoromethyl)thiazol-2-amine
4-trifluoromethylthiazol-2-ylamine
4-trifluoromethyl-2-aminothiazole
A822476
2-Amino-4-trifluoromethylthiazole
MFCD00832759
4-trifluoromethyl-thiazol-2ylamine
4-(trifluoromethyl)-1,3-thiazol-2-amine
GEO-02881
4-trifluoromethylthiazole-2ylamine
AM20090546
4-Trifluoromethyl-thiazole-2-ylamine
A6136
4-Trifluoromethyl-thiazole-2ylamine
2-Thiazolamine, 4-(trifluoromethyl)-
BB 0260033
J-513943
FT-0632003
2-amino-4-trifluoromethyl-1,3-thiazole
SCHEMBL245790
349-49-5
DTXSID80188451
AC-4447
4-(Trifluoromethyl)-2-thiazolamine
AB-601/30915004
CS-W009047
EN300-36834
4-trifluoromethyl-thiazol-2-ylamine
4-trifluoromethyl-thiazol-2-ylamine, AldrichCPR

MDL Number

MFCD00832759

Customs Code

2934100090

FAQ

What is 4-(trifluoromethyl)-1,3-thiazol-2-amine (CAS: 349-49-5)?

4-(trifluoromethyl)-1,3-thiazol-2-amine, also known as CAS 349-49-5, is an aromatic thiazol derivative with the molecular formula C5H3F3N2S. It has a distinctive odor and is a colorless to white solid at room temperature. This compound is used in various applications including pharmaceuticals, as a reagent in organic synthesis, and in some industrial processes.

What are the main uses of 4-(trifluoromethyl)-1,3-thiazol-2-amine (CAS: 349-49-5)?

4-(trifluoromethyl)-1,3-thiazol-2-amine is primarily used in the pharmaceutical industry as a precursor for synthetic drugs and in organic synthesis. It is also employed in industrial applications for its unique chemical properties, such as its reactivity with various functional groups.

Is 4-(trifluoromethyl)-1,3-thiazol-2-amine (CAS: 349-49-5) safe?

4-(trifluoromethyl)-1,3-thiazol-2-amine is generally safe when handled with appropriate precautions. Users should avoid contact with eyes and skin, and inhaling the fumes. It is advisable to work in a well-ventilated area and use personal protective equipment such as gloves and safety goggles. Keep away from heat and sources of ignition.

How should 4-(trifluoromethyl)-1,3-thiazol-2-amine (CAS: 349-49-5) be stored?

4-(trifluoromethyl)-1,3-thiazol-2-amine should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container to protect it from moisture and air. Store in a fume hood or a well-ventilated area to prevent inhalation of fumes.