Boc-D-Glu-OBzl

Basic Information

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CAS Number

34404-30-3

Molecular Formula

C17H23NO6

Molecular Weight

337.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

No data available

Melting Point

96.0 to 100.0 deg-C

Boiling Point

522.6℃ at 760 mmHg

Density

1.1970

Flash Point

269.9±30.1 °C

Vapor Pressure

0.0±1.4 mmHg at 25°C

Specific Rotation

+33.5° (c=1% in Chloroform)

SMILES

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CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)OCC1=CC=CC=C1

InChI

InChI=1S/C17H23NO6/c1-17(2,3)24-16(22)18-13(9-10-14(19)20)15(21)23-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,19,20)/t13-/m1/s1

InChIKey

CVZUKWBYQQYBTF-CYBMUJFWSA-N

LogP

2.4879000000000007

Topological Polar Surface Area

101.93 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

437

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(4R)-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxo-5-phenylmethoxypentanoic acid
AS-18955
Boc-D-glutamic acid a-benzyl ester
D-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(phenylmethyl)ester
CVZUKWBYQQYBTF-CYBMUJFWSA-N
N-tert-Butoxycarbonyl-D-glutamic acid a-benzyl ester
(4R)-5-(BENZYLOXY)-4-{[(TERT-BUTOXY)CARBONYL]AMINO}-5-OXOPENTANOIC ACID
Boc-D-Glu-OBzl
1-Benzyl N-Boc-L-glutamate
SCHEMBL2707177
Boc-D-Glu-OBn
A851411
MFCD00038266
M04117
(R)-5-(Benzyloxy)-4-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid
1-Benzyl N-Boc-D-glutamate
A820654
HY-W011201
J-300108
AC-8615
Boc-D-Glu-OBzl, >=98.0% (TLC)
B4303
CS-W011917
AM20040142
N-Boc-D-Glutamic Acid 1-Benzyl Ester
Q-101800
N-(tert-Butoxycarbonyl)-D-glutamic Acid 1-Benzyl Ester
Boc-D-glutamic acid benzyl ester
N-Boc-D-glutamic Acid Benzyl Ester
34404-30-3
CHEMBL163796

MDL Number

MFCD00038266

Customs Code

2924299090

FAQ

What is Boc-D-Glu-OBzl (CAS: 34404-30-3)?

Boc-D-Glu-OBzl is a protected amino acid derivative used in peptide synthesis. It contains a Boc (tert-butyloxycarbonyl) protecting group on the carboxylic acid of D-Glu (D-glutamic acid) and an OBzl (p-benzoylbenzyl) group on the amine. It is a key reagent in organic synthesis, particularly in the preparation of unnatural peptides and as a building block in solid-phase peptide synthesis.

What are the main uses of Boc-D-Glu-OBzl (CAS: 34404-30-3)?

Boc-D-Glu-OBzl is primarily used in the synthesis of peptides and proteins, especially in solid-phase peptide synthesis. It serves as a versatile protecting group for D-Glu and is crucial for maintaining the integrity of the amino acid during synthesis. It is also used in chemical biology, drug discovery, and as a functional group in various organic reactions.

Is Boc-D-Glu-OBzl (CAS: 34404-30-3) safe?

Boc-D-Glu-OBzl is generally safe when handled properly. However, it should be used with caution due to its potential to irritate skin and eyes. Protective gloves and goggles should be worn. It is important to follow all safety guidelines and work in a well-ventilated area. Avoid contact with skin and eyes, and handle in a fume hood when necessary.

How should Boc-D-Glu-OBzl (CAS: 34404-30-3) be stored?

Boc-D-Glu-OBzl should be stored in a tightly sealed container at a cool, dry place, preferably below 25°C. It should be protected from direct sunlight and moisture. The container should be kept away from heat sources and flammable materials. Refrigeration is not necessary but can be used to maintain stability. It is advisable to store it in a fume hood to minimize exposure to air and moisture.