1-(3-Chloro-2-pyridinyl)methanamine dihydrochloride

Basic Information

View in Editor

CAS Number

342816-31-3

Molecular Formula

C6H9Cl3N2

Molecular Weight

215.51 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Colorless to Yellow Solid

SMILES

View in Editor

Cl.Cl.NCC1=NC=CC=C1Cl

InChI

InChI=1S/C6H7ClN2.2ClH/c7-5-2-1-3-9-6(5)4-8;;/h1-3H,4,8H2;2*1H

InChIKey

OYXCTHVMOQFONQ-UHFFFAOYSA-N

LogP

2.0373

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(3-Chloropyridin-2-yl)methanamine dihydrochloride
(3-CHLORO-PYRIDIN-2-YL)-METHYL AMINE DIHYDROCHLORIDE
(3-Chloro-pyridin-2-yl)-methylamine dihychloride
2-AMINOMETHYL-3-CHLORO-PYRIDINE DIHYDROCHLORIDE
(3-CHLORO-PYRIDIN-2-YL)METHYLAMINE DIHYDROCHLORIDE
2-Aminomethyl-3-chloro-pyridine 2HCl
(3-Chloro-pyridin-2-yl)-methylamine dihydrochloride
(3-chloropyridin-2-yl)methanamine dihydrochloride

MDL Number

MFCD07371473

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 1-(3-Chloro-2-pyridinyl)methanamine dihydrochloride (CAS: 342816-31-3)?

1-(3-Chloro-2-pyridinyl)methanamine dihydrochloride is a white or off-white crystalline solid with a molecular weight of approximately 249.02 g/mol. It has a high solubility in water and is less soluble in organic solvents. This compound exhibits basic properties due to the amine group and can react with acids to form its dihydrochloride salt. It is stable under normal conditions but should be stored in a dry, cool place to avoid hydrolysis.

How is 1-(3-Chloro-2-pyridinyl)methanamine dihydrochloride (CAS: 342816-31-3) typically synthesized?

1-(3-Chloro-2-pyridinyl)methanamine dihydrochloride is typically synthesized by reacting 1-(3-chloro-2-pyridinyl)methanamine with hydrochloric acid. The reaction is carried out in a suitable solvent such as methanol or ethanol. The process involves the protonation of the amine group to form the dihydrochloride salt, yielding a high yield of product with good selectivity.

What industries use 1-(3-Chloro-2-pyridinyl)methanamine dihydrochloride (CAS: 342816-31-3)?

1-(3-Chloro-2-pyridinyl)methanamine dihydrochloride is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the chemical industry for the development of new materials, such as polymers and sensors, due to its unique chemical properties.

What precautions should be taken when handling 1-(3-Chloro-2-pyridinyl)methanamine dihydrochloride (CAS: 342816-31-3)?

When handling 1-(3-Chloro-2-pyridinyl)methanamine dihydrochloride, it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to avoid inhalation of dust or vapors. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. Always consult the safety data sheet (SDS) for specific handling instructions and emergency procedures.