N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate (1:1) | CAS No. 342595-05-5

N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate (1:1)

Basic Information

CAS Number

342595-05-5

Molecular Formula

C21H21ClN4O5

Molecular Weight

444.88 g/mol

AD

Basic Physical Properties

Solubility

Insuluble (7.3E-6 g/L) (25 ºC),

c1ccc(c(c1)NC(=O)c2cnc3n2cc(cc3)C4CCNCC4)Cl.C(=O)(C(=O)O)O

InChI

InChI=1S/C19H19ClN4O.C2H2O4/c20-15-3-1-2-4-16(15)23-19(25)17-11-22-18-6-5-14(12-24(17)18)13-7-9-21-10-8-13;3-1(4)2(5)6/h1-6,11-13,21H,7-10H2,(H,23,25);(H,3,4)(H,5,6)

InChIKey

ODBJGLKPAQMCJA-UHFFFAOYSA-N

LogP

2.8625999999999996

Topological Polar Surface Area

133.03 Ų

Hydrogen Bond Donor/Acceptor

4 / 9

Synonyms & References

English

  • TM 5007
  • TM5007
  • [2,3'-Bithiophene]-4'-carboxylic acid, 5',5'''-[(1,6-dioxo-1,6-hexanediyl)diimino]bis-

MDL Number

MFCD29770817

FAQ

What are the physical and chemical properties of N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate (CAS: 342595-05-5)?

N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate is a crystalline solid with a molecular weight of approximately 504.3 g/mol. It is poorly soluble in water but has good solubility in organic solvents such as methanol and acetonitrile. The compound is known for its reactivity in amide formation reactions and its stability under neutral to slightly acidic conditions.

How is N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate (CAS: 342595-05-5) typically synthesized?

N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate is usually synthesized through a multi-step process involving the condensation of an intermediate imidazole derivative with 2-chloro-phenyl piperidine, followed by the formation of the ethanedioate ester. Key reagents include piperidine, chlorophenyl derivatives, and ethanedioic acid. The reaction is typically carried out under mild conditions, with good selectivity and moderate to high yield.

What industries use N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate (CAS: 342595-05-5)?

N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate is primarily used in the pharmaceutical industry for the development of new drugs, particularly in the treatment of neurological disorders. It also finds applications in the field of chemical sensors and as a precursor in the synthesis of other complex organic compounds.

What precautions should be taken when handling N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate (CAS: 342595-05-5)?

When handling N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coat. Ensure the use of a fume hood during handling to avoid inhalation risks. In case of a spill, immediately clean up using appropriate absorbents and consult the Safety Data Sheet (SDS) for further guidance. Store the compound in a cool, dry place away from direct sunlight and heat sources.

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...