N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate (1:1)(CAS: 342595-05-5)

N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate is a crystalline solid with a molecular weight of approximately 504.3 g/mol. It is poorly soluble in water but has good solubility in organic solvents such as methanol and acetonitrile. The compound is known for its reactivity in amide formation reactions and its stability under neutral to slightly acidic conditions.

N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate is usually synthesized through a multi-step process involving the condensation of an intermediate imidazole derivative with 2-chloro-phenyl piperidine, followed by the formation of the ethanedioate ester. Key reagents include piperidine, chlorophenyl derivatives, and ethanedioic acid. The reaction is typically carried out under mild conditions, with good selectivity and moderate to high yield.

N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate is primarily used in the pharmaceutical industry for the development of new drugs, particularly in the treatment of neurological disorders. It also finds applications in the field of chemical sensors and as a precursor in the synthesis of other complex organic compounds.

When handling N-(2-Chlorophenyl)-6-(4-piperidinyl)imidazo[1,2-a]pyridine-3-carboxamide ethanedioate, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coat. Ensure the use of a fume hood during handling to avoid inhalation risks. In case of a spill, immediately clean up using appropriate absorbents and consult the Safety Data Sheet (SDS) for further guidance. Store the compound in a cool, dry place away from direct sunlight and heat sources.