6-Bromo-2-pyridinecarbaldehyde

Basic Information

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CAS Number

34160-40-2

Molecular Formula

C6H4BrNO

Molecular Weight

186.01 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

81-85 °C

Boiling Point

248.2℃ at 760 mmHg

Water Solubility

Soluble in dichloromethane, ether, ethyl acetate and methanol. Insoluble in water.

Flash Point

103.9℃

SMILES

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C1=CC(=NC(=C1)Br)C=O

InChI

InChI=1S/C6H4BrNO/c7-6-3-1-2-5(4-9)8-6/h1-4H

InChIKey

QWFHFNGMCPMOCD-UHFFFAOYSA-N

LogP

1.6565999999999996

Topological Polar Surface Area

29.96 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

107

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Air Sensitive

Synonyms & References

English

6-Bromo-2-Pyridine Carboxaldehyde
2-formyl-6-bromopyridine
BB 0305529
2-Pyridinecarboxaldehyde, 6-bromo-
QWFHFNGMCPMOCD-UHFFFAOYSA-N
6-bromopyridine-2-carboaldehyde
SCHEMBL104173
BCP14423
DTXSID10373691
6-bromo-2-pyridinecarbaldehyde
6-Bromo-2-formylpyridine
6-Bromo-2-formyl-pyridine
EN300-107792
W-200313
6-Bromo-2-pyridinecarboxaldehyde, 97%
AC-5124
NS00124837
PB27582
2-bromo-6-formylpyridine
6-bromopyridine-2-aldehyde
(6-bromo-2-pyridyl)-formaldehyde
6-bromo-2-pyridinealdehyde
6-Bromo-2-pyridinecarboxaldehyde
6-bromo-pyridine-2-carbaldehyde
AKOS005257664
6-Bromo-pyridin-2-carbaldehyde
AS-5650
6-bromopyridine-2-carbaldehyde
6-Bromopicoline aldehyde
2-bromo-6-pyridinecarboxaldehyde
6-bromo pyridine-2-carboxaldehyde

MDL Number

MFCD02683546

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-Bromo-2-pyridinecarbaldehyde (CAS: 34160-40-2)?

6-Bromo-2-pyridinecarbaldehyde (CAS: 34160-40-2) is a crystalline solid with a molecular weight of approximately 214.04 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly towards nucleophiles. It is an electrophilic aromatic compound and can undergo substitution reactions under certain conditions.

How is 6-Bromo-2-pyridinecarbaldehyde (CAS: 34160-40-2) typically synthesized?

6-Bromo-2-pyridinecarbaldehyde (CAS: 34160-40-2) is typically synthesized via the bromination of 2-pyridinecarbaldehyde using N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide. The reaction is performed in an organic solvent like chloroform or dichloromethane. This method provides good yields and high selectivity for the bromo group introduction.

What industries use 6-Bromo-2-pyridinecarbaldehyde (CAS: 34160-40-2)?

6-Bromo-2-pyridinecarbaldehyde (CAS: 34160-40-2) is used in the pharmaceutical industry for the synthesis of intermediates in drug development. It also finds applications in the production of dyes and pigments, as well as in the development of new materials for sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 6-Bromo-2-pyridinecarbaldehyde (CAS: 34160-40-2)?

When handling 6-Bromo-2-pyridinecarbaldehyde (CAS: 34160-40-2), appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats should be worn. This compound should be stored in a cool, dry place away from direct sunlight and flammable materials. Spills should be handled using appropriate absorbents and the Material Safety Data Sheet (MSDS) should be consulted for specific procedures. Ventilation should be ensured during handling to avoid inhalation of fumes.