N-Benzyl-2-methyl-2-propanamine

Basic Information

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CAS Number

3378-72-1

Molecular Formula

C11H17N

Molecular Weight

163.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

-25 ºC

Boiling Point

252°C

Water Solubility

2 g/L (20 ºC)

Flash Point

88 ºC

Solubility

2g/l

Refractive Index

1.496-1.498

SMILES

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CC(C)(C)NCC1=CC=CC=C1

InChI

InChI=1S/C11H17N/c1-11(2,3)12-9-10-7-5-4-6-8-10/h4-8,12H,9H2,1-3H3

InChIKey

DLSOILHAKCBARI-UHFFFAOYSA-N

LogP

2.574700000000001

Topological Polar Surface Area

12.03 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

118

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H301 Toxic if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

NS00019717
3378-72-1
FT-0657887
N-t-butyl-N-benzylamine
tert-Butylbenzylamine
N-tert-Butylbenzylamine
1060688-77-8
AI3-23247
B1176
DTXSID2063002
EINECS 222-179-6
QMD9L6C8U3
Benzyl(tert-butyl)amine
D78115
Benzenemethanamine, N-(1,1-dimethylethyl)-
N-benzyl-t-butylamine
N-t-Butylbenzylamine
N-(tert-Butyl)benzenemethanamine
N-benzyl-N-tert-butylamine
Benzyl-tert-butyl-amine
N-benzyl-N-tert.-butylamine
N-(1,1-dimethylethyl)benzenemethanamine
AC-23994
SB75737
MFCD00008798
N-(tert-Butyl)benzylamine
N-tert-butyl-N-benzylamine
N-Benzyl-2-methyl-2-propanamine #
n-benzyl-tert-butyl-d9-amine
EN300-16560
benzyl-tert-butylamine

MDL Number

MFCD00008798

Customs Code

29214980

FAQ

What are the physical and chemical properties of N-Benzyl-2-methyl-2-propanamine (CAS: 3378-72-1)?

N-Benzyl-2-methyl-2-propanamine is a clear, colorless, oily liquid with a molecular weight of 175.24 g/mol. It has a high boiling point (198-200°C) and a low melting point (-40°C). This compound is slightly soluble in water but miscible with most organic solvents. It is relatively stable under normal conditions but can react with strong oxidizing agents.

How is N-Benzyl-2-methyl-2-propanamine (CAS: 3378-72-1) typically synthesized?

N-Benzyl-2-methyl-2-propanamine is commonly synthesized via aminolysis of benzyl chloride with 2-methyl-2-propanamine. The reaction is performed in the presence of a base like sodium hydroxide. The process typically yields a 90-95% pure product with excellent selectivity. The reaction is exothermic, and careful temperature control is essential to avoid side reactions.

What industries use N-Benzyl-2-methyl-2-propanamine (CAS: 3378-72-1)?

N-Benzyl-2-methyl-2-propanamine is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of certain drugs. It is also utilized in the production of polymers, where it acts as a crosslinking agent, and in the development of chemical sensors due to its reactivity and stability characteristics.

What precautions should be taken when handling N-Benzyl-2-methyl-2-propanamine (CAS: 3378-72-1)?

When handling N-Benzyl-2-methyl-2-propanamine, appropriate personal protective equipment (PPE) including gloves, goggles, and lab coat should be worn. Store it in a cool, well-ventilated area away from direct sunlight and heat sources. Use a fume hood during handling and disposal. In case of spills, use appropriate cleanup materials, and consult the Safety Data Sheet (SDS) for specific procedures.