3-Amino-2,2-dimethylpropanamide

Basic Information

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CAS Number

324763-51-1

Molecular Formula

C5H12N2O

Molecular Weight

116.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

74-75 ºC

Boiling Point

271 ºC

Flash Point

117 ºC

SMILES

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CC(C)(CN)C(=O)N

InChI

InChI=1S/C5H12N2O/c1-5(2,3-6)4(7)8/h3,6H2,1-2H3,(H2,7,8)

InChIKey

HKQZJXVIXAPOPZ-UHFFFAOYSA-N

LogP

-0.5433999999999994

Topological Polar Surface Area

69.11 Å²

Hydrogen Bond Donor/Acceptor

4 / 3

Complexity

98.6

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

FT-0647546
BCP04929
AB00999687-01
PB29404
3-Amino-2 pound not2-dimethylpropionamide
AKOS009580115
GS-4402
3-AMINO-2,2-DIMETHYLPROPIONAMIDE
1246820-97-2
3-amino-2,2-di(methyl)propionamide
Z431519836
3-Amino-2,2-dimethyl-propionamide;3-AMINO-2,2-DIMETHYLPROPANAMIDE
Propanamide, 3-amino-2,2-dimethyl-
AC-8492
Q-102799
Aliskiren metabolite M9 2
HKQZJXVIXAPOPZ-UHFFFAOYSA-N
EN300-42683
NS00077817
SY021307
3-amino-2,2-dimethylpropanamide
MFCD06797568
DTXSID30457149
CS-W003343
AM20090472
3-Amino-2,2-dimethyl-propionamide
SCHEMBL188468
A5817
324763-51-1
3-Amino-2,2-dimethylpropionamide
3-Amino-2,2-dimethylpropanamide

MDL Number

MFCD06797568

Customs Code

2924199090

FAQ

What are the physical and chemical properties of 3-Amino-2,2-dimethylpropanamide (CAS: 324763-51-1)?

3-Amino-2,2-dimethylpropanamide is a colorless or white crystalline solid with a molecular weight of 138.15 g/mol. It has a pKa of 8.7 and is slightly soluble in water. It exhibits basic properties due to the amino group and is stable under normal conditions but can react with strong acids to form amides. It has a melting point of 96-98°C and is sparingly soluble in ethanol and acetone.

How is 3-Amino-2,2-dimethylpropanamide (CAS: 324763-51-1) typically synthesized?

3-Amino-2,2-dimethylpropanamide can be synthesized by reacting dimethyl acetamide with ammonia in the presence of a catalyst, such as p-toluenesulfonic acid. The reaction is carried out under mild conditions, and the product is isolated by recrystallization. The yield is typically around 70-80%. Other methods involve the condensation of dimethyl acetamide with hydroxylamine followed by reduction to form the amide.

What industries use 3-Amino-2,2-dimethylpropanamide (CAS: 324763-51-1)?

3-Amino-2,2-dimethylpropanamide is used in the pharmaceutical industry as an intermediate in the synthesis of drugs, particularly in the production of beta-lactam antibiotics. It is also utilized in the polymer industry for the preparation of novel polymeric materials with specific properties. Additionally, it has applications in the sensor technology sector and as a reagent in various analytical and chemical processes.

What precautions should be taken when handling 3-Amino-2,2-dimethylpropanamide (CAS: 324763-51-1)?

When handling 3-Amino-2,2-dimethylpropanamide, proper personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight. Spills should be handled using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed precautions and emergency procedures.