7-Fluoro-1H-indole-2,3-dione

Basic Information

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CAS Number

317-20-4

Molecular Formula

C8H4FNO2

Molecular Weight

165.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Physical State

Light-red to Brown Solid

Melting Point

193.0 to 197.0 deg-C

Density

1.502

Water Solubility

Sparingly Soluble in water (0.022 g/L)

Refractive Index

1.56

SMILES

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C1=CC2=C(C(=C1)F)NC(=O)C2=O

InChI

InChI=1S/C8H4FNO2/c9-5-3-1-2-4-6(5)10-8(12)7(4)11/h1-3H,(H,10,11,12)

InChIKey

HGBGVEOXPHGSOS-UHFFFAOYSA-N

LogP

0.9604999999999999

Topological Polar Surface Area

46.17 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

241

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

7-fluoro- 1H-indole-2,3-dione
SY009282
7-Fluoro-1H-indole-2,3-dione
Isatin-based compound, 42
7-Fluoro-2,3-dihydro-1H-indol-2,3-dione
7-Fluoro-1H-indole-2,3-dione;7-Fluoroisatin
317-20-4
7-fluoro-2,3-indolinedione
7-Fluoro-1H-indol-2,3-dione
7-Fluoroisatin, 96%
AM20060261
7-fluoro-2,3-dihydro-1H-indole-2,3-dione
7-Fluoroisatin Form I
1H-Indole-2,3-dione, 7-fluoro-
7-Fluoro-1H-indole-2,3-dione #
AC-439
F-5610
7-Fluoroindole-2,3-dione
HGBGVEOXPHGSOS-UHFFFAOYSA-
InChI=1/C8H4FNO2/c9-5-3-1-2-4-6(5)10-8(12)7(4)11/h1-3H,(H,10,11,12)
AB09245
7-Fluoroindole-1H-2,3-dione
7-fluoroindoline-2,3-dione
BDBM22822
7-Fluoroisatin
7-fluoro-1 H-indole-2,3-dione
SCHEMBL281604
FT-0602157
MFCD01569508
BCP21682
DTXSID90342986

MDL Number

MFCD01569508

Customs Code

2933990090

FAQ

What regulatory guidelines apply to 7-Fluoro-1H-indole-2,3-dione (CAS: 317-20-4)?

7-Fluoro-1H-indole-2,3-dione (CAS: 317-20-4) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a hazardous chemical. Manufacturers and distributors must comply with REACH regulations for registration, evaluation, and authorization of substances. Additionally, the FDA and EPA have specific guidelines for handling and reporting of this compound in the United States. Proper labeling, documentation, and storage are essential to ensure compliance with all relevant regulations.

Are there alternatives to 7-Fluoro-1H-indole-2,3-dione (CAS: 317-20-4) in synthesis?

There are several alternatives to 7-Fluoro-1H-indole-2,3-dione (CAS: 317-20-4) in synthesis, such as 7-chloro-1H-indole-2,3-dione and 7-bromo-1H-indole-2,3-dione. These compounds can be used as isomers or analogs depending on the desired properties. Other common alternative reagents include indole-2,3-dione and 7-aminomethyl-1H-indole-2,3-dione, which can be more readily available or have different reactivity profiles, thus offering flexibility in synthetic pathways.

What is the market or research trend for 7-Fluoro-1H-indole-2,3-dione (CAS: 317-20-4)?

The market for 7-Fluoro-1H-indole-2,3-dione (CAS: 317-20-4) is currently growing due to its potential applications in pharmaceutical research, particularly in the development of novel drugs targeting various diseases. Research trends indicate a focus on its use as a precursor for synthesizing bioactive compounds. The price trend shows fluctuations based on demand and supply, while emerging research fields are exploring its role in medicinal chemistry and drug discovery.

How should waste containing 7-Fluoro-1H-indole-2,3-dione (CAS: 317-20-4) be handled?

Waste containing 7-Fluoro-1H-indole-2,3-dione (CAS: 317-20-4) should be handled according to hazardous waste regulations. Waste liquid should be collected and disposed of using professional waste disposal services. Incineration is another option for disposal, but this must be conducted in a controlled environment. Environmental protection measures include proper containment to prevent spillage, and appropriate personal protective equipment (PPE) should be worn to ensure the safety of all personnel involved in the handling and disposal process.