5-Hydroxymethyluridine

Basic Information

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CAS Number

30414-00-7

Molecular Formula

C10H14N2O7

Molecular Weight

274.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

167-168 ºC

SMILES

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C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)CO

InChI

InChI=1S/C10H14N2O7/c13-2-4-1-12(10(18)11-8(4)17)9-7(16)6(15)5(3-14)19-9/h1,5-7,9,13-16H,2-3H2,(H,11,17,18)/t5-,6-,7-,9-/m1/s1

InChIKey

VQAJJNQKTRZJIQ-JXOAFFINSA-N

LogP

-3.3595999999999995

Topological Polar Surface Area

145.01 Å²

Hydrogen Bond Donor/Acceptor

5 / 9

Complexity

424

Synonyms & References

English

SCHEMBL263750
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione
5-Hydroxymethyluridine
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione
5-Hydroxymethyl ?uridine
A848737
4-Hydroxy-5-(hydroxymethyl)-1-pentofuranosylpyrimidin-2(1H)-one
DTXSID00952752
AKOS027339888
CHEBI:165841
F12671
1-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione;
30414-00-7
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
5-(hydroxymethyl)uridine
MFCD00057401
Uridine,5-(hydroxymethyl)- (6CI,7CI,8CI,9CI)
5-(Hydroxymethyl)uridine
2-Hydroxymethylthiophene-5-carboxylic acid ethyl ester
5-hydroxymethyl-thiophene-2-carboxylic acid ethyl ester
5-Hydroxymethyl-uridin
5-hydroxymethyl-uridine
ethyl 5-hydroxymethylthiophene-2-carboxylate
MB07582
SureCN2653117
Uridin-5-methanol

MDL Number

MFCD00057401

FAQ

What regulatory guidelines apply to 5-Hydroxymethyluridine (CAS: 30414-00-7)?

5-Hydroxymethyluridine (CAS: 30414-00-7) requires adherence to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations, and FDA/EPA guidelines for chemical substances. Specific safety data sheets (SDS) should be consulted for detailed handling and storage instructions.

Are there alternatives to 5-Hydroxymethyluridine (CAS: 30414-00-7) in synthesis?

Yes, alternative reagents such as 5-methyluridine or 5-azauridine can be used as substitutes in the synthesis of RNA analogs. Researchers often explore these alternatives to achieve specific chemical properties or to avoid potential toxicity issues.

What is the market or research trend for 5-Hydroxymethyluridine (CAS: 30414-00-7)?

The market for 5-Hydroxymethyluridine (CAS: 30414-00-7) is driven by its use in RNA research and therapeutic applications. Recent trends indicate growing interest in RNA modifications and editing technologies, which could further boost demand. Research is also focusing on the development of new derivatives with enhanced specificity and stability.

How should waste containing 5-Hydroxymethyluridine (CAS: 30414-00-7) be handled?

Waste containing 5-Hydroxymethyluridine (CAS: 30414-00-7) should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration is a common method, and environmental precautions, such as proper containment and emission control, should be followed to minimize environmental impact.