2-Methyl-3-butyn-2-amine

Basic Information

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CAS Number

2978-58-7

Molecular Formula

C5H9N

Molecular Weight

73.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Physical Properties

Melting Point

18°C

Boiling Point

79-80 °C/760 mmHg

Water Solubility

Very soluble in water.

Refractive Index

n20/D 1.4237

SMILES

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CC(C)(C#C)N

InChI

InChI=1S/C5H9N/c1-4-5(2,3)6/h1H,6H2,2-3H3

InChIKey

VUGCBIWQHSRQBZ-UHFFFAOYSA-N

LogP

0.7436

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

83.4

Safety Information

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Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Hazard Class

Class 3 (8) Class 3 (8)

Sensitiveness

Air Sensitive

Synonyms & References

English

1,1-Dimethylprop-2-ynylamine
J-503744
1,1-dimethypropinylamine
BB 0216326
EN300-72142
2-Methyl-3-butyn-2-amine, 95%
2-methyl-3-butin-2-yl-amin
EINECS 221-029-7
DTXSID1062752
3-Amino-3-methyl-1-butyne
3-amino-3-methylbut-1-yne
1H-Pyrrole-2,5-dione, 1-[4-(1-methylethyl)phenyl]-
1,1-Dimethylprop-3-ynylamine
dimethylprop-2-yn-1-amine
3-amino-3-methylbutyne
1,1-Dimethylpropargylamine
3-Butyn-2-amine, 2-methyl-
AT19954
2-methyl-but-3-in-2-yl-amine
3-amino-3, 3-dimethyl-1-propine
AMY19729
HC=CCMe2NH2
2-Propynylamine, 1,1-dimethyl-
FT-0600471
30-D-11
1,1-Dimethyl-2-propynylamine #
AKOS000320670
NS00009249
2-methylbut-3-yn-2-amine
1,1-Dimethyl-prop-2-ynylamine
STR09786

MDL Number

MFCD00008052

Customs Code

2921199090

FAQ

What are the physical and chemical properties of 2-Methyl-3-butyn-2-amine (CAS: 2978-58-7)?

2-Methyl-3-butyn-2-amine is a liquid at room temperature with a molecular weight of approximately 85.12 g/mol. It has a low solubility in water but is soluble in organic solvents. It is moderately reactive and can undergo electrophilic addition reactions. The compound is flammable and highly toxic by inhalation and skin contact.

How is 2-Methyl-3-butyn-2-amine (CAS: 2978-58-7) typically synthesized?

2-Methyl-3-butyn-2-amine is typically synthesized by the reaction of 3-butyne with methylamine in the presence of a catalyst, such as palladium or platinum. The process involves electrophilic addition followed by amination. The yield is usually around 70-80%, and the method is selective for the desired product.

What industries use 2-Methyl-3-butyn-2-amine (CAS: 2978-58-7)?

2-Methyl-3-butyn-2-amine is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those involving alkyne functionalities. It is also utilized in the polymer industry for the production of specialty polymers, and in the sensor industry for the development of gas sensors.

What precautions should be taken when handling 2-Methyl-3-butyn-2-amine (CAS: 2978-58-7)?

When handling 2-Methyl-3-butyn-2-amine, proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat is essential. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up carefully using appropriate absorbents, and the area should be well-ventilated. Safety data sheets (SDS) should be consulted for detailed emergency procedures and storage guidelines.