5-Bromonicotinamide

Basic Information

View in Editor

CAS Number

28733-43-9

Molecular Formula

C6H5BrN2O

Molecular Weight

201.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

218.0 to 223.0 deg-C

Boiling Point

315.5℃ at 760 mmHg

Density

1.71

Flash Point

144.6℃

Refractive Index

1.613

SMILES

View in Editor

C1=C(C=NC=C1Br)C(=O)N

InChI

InChI=1S/C6H5BrN2O/c7-5-1-4(6(8)10)2-9-3-5/h1-3H,(H2,8,10)

InChIKey

YOQRXZIMSKLRCY-UHFFFAOYSA-N

LogP

0.9429999999999998

Topological Polar Surface Area

55.980000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

140

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

NS00068205
3-Pyridinecarboxamide, 5-bromo-
CS-W015578
5-bromopyridine-3-carboxamide
EN300-1232895
PD008723
BRN 0115921
UNII-FCT9J0CUP7
Nicotinamide, 5-bromo-
MFCD00173919
SY001775
BRT
5-Bromo-nicotinamide
FCT9J0CUP7
3-Bromo-5-carbamoylpyridine
5-Bromo-3-pyridinecarboxamide, 97%
B3536
FT-0638801
Z33546660
5-22-02-00182 (Beilstein Handbook Reference)
SCHEMBL578591
HMS3604K17
BCP27010
FS-2677
AM20051040
A15454
Q27092981
5-bromo-3-pyridinylcarboxamide
5-bromonicotinamide
28733-43-9
BB 0244175

MDL Number

MFCD00173919

Customs Code

2933399090

FAQ

What regulatory guidelines apply to 5-Bromonicotinamide (CAS: 28733-43-9)?

5-Bromonicotinamide (CAS: 28733-43-9) is regulated under the Globally Harmonized System (GHS) for Classification and Labeling of Chemicals. It is classified as a substance with toxicity and may require reporting under REACH regulations for substances above one tonne per year. FDA and EPA may also have specific requirements for its use and handling in the United States.

Are there alternatives to 5-Bromonicotinamide (CAS: 28733-43-9) in synthesis?

Alternatives to 5-Bromonicotinamide in synthesis include other aromatic amines such as 5-chloronicotinamide and nicotinamide. Isomers like 6-bromonicotinamide or other functionalized analogs might also be considered based on the desired properties and reactivity. Common reagents for synthesis include bromine and other halogenating agents.

What is the market or research trend for 5-Bromonicotinamide (CAS: 28733-43-9)?

Research trends for 5-Bromonicotinamide (CAS: 28733-43-9) indicate a focus on its use as a precursor in organic synthesis and in drug discovery. Market trends suggest increasing demand in academic and industrial settings, driven by its applications in medicinal chemistry and pharmaceutical development. However, its use is relatively niche and subject to regulatory scrutiny.

How should waste containing 5-Bromonicotinamide (CAS: 28733-43-9) be handled?

Waste containing 5-Bromonicotinamide (CAS: 28733-43-9) should be collected in appropriate containers and stored separately. It can be incinerated or disposed of through professional waste disposal services that comply with local and international regulations. Environmental protection measures include ensuring proper labeling and minimizing exposure during handling to prevent contamination of soil and water sources.