NIGERICIN SODIUM SALT

Basic Information

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CAS Number

28380-24-7

Molecular Formula

C40H68O11

Molecular Weight

724.97 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

183-185 ºC

Specific Rotation

D24 +36.2° (c = 0.842 in CHCl3)

SMILES

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CC1CCC(OC1C(C)C(=O)O)CC2CC(C(C3(O2)C(CC(O3)(C)C4CCC(O4)(C)C5C(CC(O5)C6C(CC(C(O6)(CO)O)C)C)C)C)C)OC

InChI

InChI=1S/C40H68O11/c1-21-11-12-28(46-33(21)26(6)36(42)43)17-29-18-30(45-10)27(7)40(48-29)25(5)19-38(9,51-40)32-13-14-37(8,49-32)35-23(3)16-31(47-35)34-22(2)15-24(4)39(44,20-41)50-34/h21-35,41,44H,11-20H2,1-10H3,(H,42,43)/t21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34-,35+,37-,38-,39-,40+/m0/s1

InChIKey

DANUORFCFTYTSZ-SJSJOXFOSA-N

LogP

5.705600000000007

Topological Polar Surface Area

142.37 Å²

Hydrogen Bond Donor/Acceptor

3 / 11

Complexity

1230

Safety Information

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Hazard Class

Class 6.1(b) Class 6.1(b)

Toxicity

LD50 in mice (mg/kg): 10-15 i.p. (Shoji); also reported as 2.5 i.p. (Harned)

Synonyms & References

English

X-464
NS00010273
CHEBI:7569
(2R)-2-[(2R,3S,6R)-6-[[(1R,3S,5R,6R,7R,9R)-3-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]-5-methyl-tetrahydrofuran-2-yl]-7-methoxy-1,3,6-trimethyl-4,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-methyl-tetrahydropyran-2-yl]propanoic acid
HMS1989P21
HY-127019
SR-05000002332
(2R)-2-[(2R,3S,6R)-6-[[(2S,4R,5R,6R,7R,9R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-methyloxan-2-yl]propanoic acid
Antibiotic K178;Antibiotic X464
DTXSID9041079
CA-421
AKOS040742303
BSPBio_001599
Helixin C
Azalomycin M
nigericin
SCHEMBL149611
CS-0091495
Antibiotic K 178
UNII-RRU6GY95IS
CHEMBL405862
Antibiotic X-464
(2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-{(2S,2'R,3'S,5R,5'R)-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-2,3'-dimethyloctahydro-2,2'-bifuran-5-yl}-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl]methyl}-3-methyltetrahydro-2H-pyran-2-yl]propanoic acid
28643-80-3
Helix C
HMS3402P21
DB14056
BRN 1696755
Q7033077
NSC292567
RRU6GY95IS

MDL Number

MFCD30377206

FAQ

What is Nigericin Sodium Salt (CAS: 28380-24-7)?

Nigericin Sodium Salt (CAS: 28380-24-7) is a derivative of the antibiotic Nigericin, commonly used in pharmaceuticals and research. It is a white powder with a melting point of approximately 255°C.

What are the main uses of Nigericin Sodium Salt (CAS: 28380-24-7)?

Nigericin Sodium Salt (CAS: 28380-24-7) is primarily used as an ionophore in research for studying membrane potentials and as a component in certain pharmaceutical formulations. It is also used in food additives and preservation.

Is Nigericin Sodium Salt (CAS: 28380-24-7) safe?

Nigericin Sodium Salt (CAS: 28380-24-7) is considered safe when used as directed. However, it should be handled with care due to its potential irritant properties. Protective gloves and goggles are recommended during handling.

How should Nigericin Sodium Salt (CAS: 28380-24-7) be stored?

Nigericin Sodium Salt (CAS: 28380-24-7) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture absorption.