Chloro(difluoro)acetic anhydride

Basic Information

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CAS Number

2834-23-3

Molecular Formula

C4Cl2F4O3

Molecular Weight

242.94 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Specialty Chemicals UV Stabilizers

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

96-97 °C

Water Solubility

Slightly Soluble in water. (1.4 g/L) (25°C)

Flash Point

25.9±15.1 ºC,

Refractive Index

n20/D 1.347(lit.)

SMILES

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C(=O)(C(F)(F)Cl)OC(=O)C(F)(F)Cl

InChI

InChI=1S/C4Cl2F4O3/c5-3(7,8)1(11)13-2(12)4(6,9)10

InChIKey

VBJIFLOSOQGDRZ-UHFFFAOYSA-N

LogP

1.7194

Topological Polar Surface Area

43.370000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

218

Safety Information

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GHS Hazard Pictograms

H301

H312

H314

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Lachrymatory

Synonyms & References

English

(2-chloro-2,2-difluoroacetyl) 2-chloro-2,2-difluoroacetate
AMY3629
2834-23-3
DTXSID3062659
Chloro(difluoro)acetic anhydride
AKOS000121327
Chlorodifluoroacetic anhydride
Acetic acid, 2-chloro-2,2-difluoro-, 1,1'-anhydride
CHLORODIFLUOROACETICANHYDRIDE
Chlorodifluoroacetic anhyride
NS00048727
Acetic acid, chlorodifluoro-, anhydride
chlorodifluoroacetic acid anhydride
MFCD00000774
FD2050
2-chloro-2,2-difluoroacetic anhydride
EINECS 220-603-4
FT-0623646
Q-102556
Chlorodifluoroacetic anhydride, 98%
SCHEMBL317358
chlorodifluoroacetic anhydride
2-chloro-2,2-difluoroacetyl 2-chloro-2,2-difluoroacetate
Acetic acid,chlorodifluoro-,anhydride
Carbonylchlorohydridotris(triphenylphosphine)rutheniuM(II)
chlorodifluoroacetic anyhydride
difluorochloroacetic anhydride
Difluorochloroacetic anhydride

MDL Number

MFCD00000774

Customs Code

2915900090

FAQ

What regulatory guidelines apply to Chloro(difluoro)acetic anhydride (CAS: 2834-23-3)?

Chloro(difluoro)acetic anhydride (CAS: 2834-23-3) is classified under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a Category 1A skin corrosion/irritation agent. In the European Union, it falls under REACH regulations, requiring suppliers to register substances above 1 tonne per year. The FDA and EPA have specific requirements for the handling, storage, and disposal of this compound, emphasizing its potential for skin and eye irritation, and the need for proper labeling and safety data sheets.

Are there alternatives to Chloro(difluoro)acetic anhydride (CAS: 2834-23-3) in synthesis?

Alternative reagents like trifluoroacetic anhydride can be used as substitutes in some synthetic processes. However, the choice of alternative depends on the specific requirements of the reaction. For instance, trifluoroacetic anhydride is a more commonly used alternative due to its similar reactivity and better solubility in organic solvents. It is important to evaluate the compatibility and efficiency of these alternatives in the specific context of the synthesis.

What is the market or research trend for Chloro(difluoro)acetic anhydride (CAS: 2834-23-3)?

The market for Chloro(difluoro)acetic anhydride (CAS: 2834-23-3) is driven by its use in the synthesis of pharmaceuticals and agrochemicals. Recent research trends indicate a growing interest in developing more environmentally friendly and safer alternatives. There is also an increasing focus on understanding the toxicological profiles of such compounds and exploring their potential applications in new materials and polymers.

How should waste containing Chloro(difluoro)acetic anhydride (CAS: 2834-23-3) be handled?

Waste containing Chloro(difluoro)acetic anhydride (CAS: 2834-23-3) should be collected in appropriate containers and stored in a well-ventilated area away from incompatible materials. It is essential to ensure that the waste is properly neutralized and treated to minimize environmental impact. Incineration is a common disposal method, provided that the facility is equipped to handle hazardous waste. Professional waste disposal services are recommended to ensure compliance with regulations and environmental safety.