Methyl (2-methoxyphenyl)acetate

Basic Information

View in Editor

CAS Number

27798-60-3

Molecular Formula

C10H12O3

Molecular Weight

180.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Refractive Index

1.5160-1.5200

SMILES

View in Editor

COC1=CC=CC=C1CC(=O)OC

InChI

InChI=1S/C10H12O3/c1-12-9-6-4-3-5-8(9)7-10(11)13-2/h3-6H,7H2,1-2H3

InChIKey

BNQRSYFOIRGRKV-UHFFFAOYSA-N

LogP

1.4106999999999998

Topological Polar Surface Area

35.53 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

168

Synonyms & References

English

AKOS000296288
2-Methoxyphenylacetic Acid Methyl Ester
(2-Methoxy-phenyl)-acetic acid methyl ester
NSC 245109
FT-0638724
NSC245109
NSC-245109
K3NWF99XPP
s11983
methyl 2-(2-methoxyphenyl)acetate
CBA79860
A819197
Acetic acid, (o-methoxyphenyl)-, methyl ester
2-Methoxyphenylacetic acid methyl
Methyl 2-methoxy-benzeneacetate
CS-0083149
SCHEMBL6554270
AM84149
2-Hydroxyphenylacetic acid, methyl ether, methyl ester
NS00028369
methyl a-methoxyphenylacetate
Methyl 2-methoxybenzeneacetate
M1329
Methyl o-methoxyphenylacetate
SY053750
AS-66129
DTXSID60182119
Methyl (2-methoxyphenyl)acetate
Benzeneacetic acid, 2-methoxy-, methyl ester
(2-methoxyphenyl)acetic acid methyl ester
Methyl 2-Methoxyphenylacetate

MDL Number

MFCD02093479

Customs Code

2918990090

FAQ

What are the physical and chemical properties of Methyl (2-methoxyphenyl)acetate (CAS: 27798-60-3)?

Methyl (2-methoxyphenyl)acetate (CAS: 27798-60-3) is a colorless to light yellow liquid with a molecular weight of approximately 168.19 g/mol. It has a low solubility in water but is very soluble in organic solvents like ethanol and acetone. This compound is reactive towards bases and can undergo hydrolysis under basic conditions. It is also prone to oxidation in air, which may affect its stability.

How is Methyl (2-methoxyphenyl)acetate (CAS: 27798-60-3) typically synthesized?

Methyl (2-methoxyphenyl)acetate (CAS: 27798-60-3) can be synthesized by the esterification of 2-methoxybenzaldehyde with acetic acid in the presence of a strong acid catalyst, such as sulfuric acid. The reaction is typically carried out under reflux conditions, and the product is purified by distillation. The process yields high purity material, and the reaction is selective for the formation of the desired ester.

What industries use Methyl (2-methoxyphenyl)acetate (CAS: 27798-60-3)?

Methyl (2-methoxyphenyl)acetate (CAS: 27798-60-3) is primarily used in the pharmaceutical and fragrance industries as a precursor for the synthesis of other compounds. It is also utilized in the polymer industry as a plasticizer. Additionally, it can be used in the production of certain dyes and as a solvent in analytical chemistry.

What precautions should be taken when handling Methyl (2-methoxyphenyl)acetate (CAS: 27798-60-3)?

When handling Methyl (2-methoxyphenyl)acetate (CAS: 27798-60-3), it is essential to wear appropriate personal protective equipment (PPE), such as gloves and safety goggles. Store the compound in a cool, well-ventilated area away from sources of heat and ignition. Use a fume hood during handling to minimize exposure. In case of a spill, neutralize the acid with a basic solution and follow the safety data sheet (SDS) for proper disposal. Always have an emergency eyewash and shower available in the work area.