2-(2-Methyl-1H-indol-3-yl)ethanamine

Basic Information

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CAS Number

2731-06-8

Molecular Formula

C11H14N2

Molecular Weight

174.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

106.0 to 110.0 deg-C

Boiling Point

177°C/1.5mmHg

Density

1.126

Flash Point

194.4°C

Refractive Index

1.65

SMILES

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Cc1[nH]c2ccccc2c1CCN

InChI

InChI=1S/C11H14N2/c1-8-9(6-7-12)10-4-2-3-5-11(10)13-8/h2-5,13H,6-7,12H2,1H3

InChIKey

CPVSLHQIPGTMLH-UHFFFAOYSA-N

LogP

1.9775199999999997

Topological Polar Surface Area

41.81 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

170

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-(2-Methyl-1H-indol-3-yl)ethanamine
ART-CHEM-BB B006949
2-Methylindole-3-ethylamine
2-METHYL TRYPTAMINE
AKOS B006949
RARECHEM AN KA 1106
1H-Indole-3-ethanamine, 2-methyl-
2-methyl-1H-Indole-3-ethanamine
1H-Indole-3-ethanamine,2-methyl
2-Methyl-1H-indole-3-ethylamine
3-(2-Aminoethyl)-2-methylindole
2-(2-Methyl-1H-indol-3-yl)-ethylamine
2-Methyltryptamine
2-(2-methyl-1H-indol-3-yl)ethan-1-amine
CPVSLHQIPGTMLH-UHFFFAOYSA-N
Q63392397
2-(2-methylindol-3-yl)ethylamine
2-Methyltryptamin
Cambridge id 5112300
TimTec1_002997
Oprea1_321802
Oprea1_726612
MLS000122004

MDL Number

MFCD00130185

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-(2-Methyl-1H-indol-3-yl)ethanamine (CAS: 2731-06-8)?

2-(2-Methyl-1H-indol-3-yl)ethanamine (CAS: 2731-06-8) is a crystalline solid with a molecular weight of approximately 216.29 g/mol. It is sparingly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound exhibits basic behavior due to the amine group and shows limited reactivity under normal conditions.

How is 2-(2-Methyl-1H-indol-3-yl)ethanamine (CAS: 2731-06-8) typically synthesized?

2-(2-Methyl-1H-indol-3-yl)ethanamine is typically synthesized via the reaction of 2-methylindole with ethylamine in the presence of a base such as sodium hydroxide. The process involves heating the mixture to promote the amide formation, followed by acidification to precipitate the amine. The yield is generally around 70-80%, with good selectivity towards the desired product.

What industries use 2-(2-Methyl-1H-indol-3-yl)ethanamine (CAS: 2731-06-8)?

2-(2-Methyl-1H-indol-3-yl)ethanamine (CAS: 2731-06-8) is primarily used in the pharmaceutical industry for the synthesis of various drug candidates. It also finds applications in the development of sensors and semiconductors due to its unique electronic and structural properties.

What precautions should be taken when handling 2-(2-Methyl-1H-indol-3-yl)ethanamine (CAS: 2731-06-8)?

When handling 2-(2-Methyl-1H-indol-3-yl)ethanamine (CAS: 2731-06-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle the compound in a well-ventilated area or a fume hood to avoid inhalation of fumes. In case of a spill, immediately clean up with appropriate materials and seek advice from a safety data sheet (SDS) for further guidance.