Paracetamol (Acetaminophen) EP Impurity H

Basic Information

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CAS Number

2623-33-8

Molecular Formula

C10H11NO3

Molecular Weight

193.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

153.0 to 157.0 deg-C

Boiling Point

329.41°C (rough estimate)

Flash Point

181.4±23.2 °C

Refractive Index

1.5300 (estimate)

SMILES

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CC(=O)NC1=CC=C(C=C1)OC(=O)C

InChI

InChI=1S/C10H11NO3/c1-7(12)11-9-3-5-10(6-4-9)14-8(2)13/h3-6H,1-2H3,(H,11,12)

InChIKey

UJAOSPFULOFZRR-UHFFFAOYSA-N

LogP

1.5702999999999998

Topological Polar Surface Area

55.4 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

219

Safety Information

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GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

NSC33893
P-ACETOXYACETANILIDE
F3228-0190
HMS3264O15
EN300-7392397
SMR002530013
4-(Acetylamino)phenyl Acetate (N,O-Diacetyl-4-aminophenol)
NSC758889
DTXCID0026256
3-(4-METHYLBENZOYL)ACRYLICACID
SBI-0207076.P001
HMS559B16
2623-33-8
DTXSID2046256
Acetamide, N-(4-(acetyloxy)phenyl)-
PARACETAMOL IMPURITY H [EP IMPURITY]
Q27274637
AG-670/32634053
Maybridge1_006198
MFCD00059205
4'-Acetoxyacetanilide
Pharmakon1600-01504515
SCHEMBL863106
VU0606051-1
NS00028061
4-Acetamidophenyl acetate
O,N-Diacetyl-4-aminophenol
NSC6083
AS-48014
SR-01000872731-1
HY-66004

MDL Number

MFCD00059205

Customs Code

2924299090

FAQ

What regulatory guidelines apply to Paracetamol (CAS: 2623-33-8)?

Paracetamol (CAS: 2623-33-8) is subject to numerous regulatory guidelines including the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), REACH regulations, and FDA and EPA requirements for pharmaceutical and chemical substances. Compliance with these guidelines ensures safe handling, storage, and transportation of the compound.

Are there alternatives to Paracetamol (CAS: 2623-33-8) in synthesis?

While Paracetamol (CAS: 2623-33-8) is a common analgesic, alternatives in synthesis include various NSAIDs (Nonsteroidal Anti-Inflammatory Drugs) and other analgesics such as ibuprofen. These alternatives may offer different pharmacological profiles and are often used depending on the specific application and regulatory requirements.

What is the market or research trend for Paracetamol (CAS: 2623-33-8)?

The market for Paracetamol (CAS: 2623-33-8) is stable, with ongoing research focusing on its efficacy and safety in various formulations. Recent trends include the development of extended-release formulations and the exploration of its use in combination therapies. Price trends are generally stable, but can fluctuate based on supply and demand dynamics.

How should waste containing Paracetamol (CAS: 2623-33-8) be handled?

Waste containing Paracetamol (CAS: 2623-33-8) should be collected in appropriate containers and disposed of through professional waste disposal services to ensure compliance with environmental regulations. Incineration or other professional waste treatment methods should be employed to prevent environmental contamination. Proper precautions should be taken to protect the environment and human health during disposal.