Sparsentan | CAS No. 254740-64-2

Sparsentan

Basic Information

View in Editor

CAS Number

254740-64-2

Molecular Formula

C32H40N4O5S

Molecular Weight

592.76 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

148 ºC (isopropanol water )

Solubility

Insuluble (1.9E-4 g/L) (25 ºC),

SMILES

View in Editor

CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC(=C(C=C3)C4=CC=CC=C4S(=O)(=O)NC5=NOC(=C5C)C)COCC

InChI

InChI=1S/C32H40N4O5S/c1-5-7-14-29-33-32(17-10-11-18-32)31(37)36(29)20-24-15-16-26(25(19-24)21-40-6-2)27-12-8-9-13-28(27)42(38,39)35-30-22(3)23(4)41-34-30/h8-9,12-13,15-16,19H,5-7,10-11,14,17-18,20-21H2,1-4H3,(H,34,35)

InChIKey

WRFHGDPIDHPWIQ-UHFFFAOYSA-N

LogP

6.539440000000007

Topological Polar Surface Area

114.10000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 9

Complexity

1060

Synonyms & References

English

RE 201
[1,1'-BIPHENYL]-2-SULFONAMIDE, 4'-[(2-BUTYL-4-OXO-1,3-DIAZASPIRO[4.4]NON-1-EN-3-YL)METHYL]-N-(4,5-DIMETHYL-3-ISOXAZOLYL...
2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl)benzenesulfonamide
4-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-N-(4,5-dimethyl-3-isoxazolyl)-2-(ethoxymethyl) [1,1-biphenyl]-2-sulfonamide
Sparsentan(RE-021)
Sparsentan-D5(RE-021-D5)
BMS-346567
DARA-a
PS433540
RE-021
Sparsentan
esparsentan
AC-35179
Sparsentan (RE-021)
[1,1'-Biphenyl]-2-sulfonamide, 4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-N-(4,5-dimethyl-3-isoxazolyl)-2'-(ethoxymethyl)-
L023324
D11776
A858308
AKOS040758741
DARA
BDBM50175523
CS-7947
F77045
9242RO5URM
254740-64-2
CHEMBL539423
PS-433540
SPARSENTAN [WHO-DD]
Sparsentan(PS433540)?
Sparsentan (USAN/INN)
4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl)-2'-(ethoxymethyl)[biphenyl]-2-sulfonamide

MDL Number

MFCD16628036

FAQ

What regulatory guidelines apply to sparsentan (CAS: 254740-64-2)?

Sparsentan (CAS: 254740-64-2) is subject to various regulatory guidelines including GHS classification for its health and environmental hazards. It falls under the scope of REACH regulations in Europe, requiring registration and reporting. FDA and EPA have specific requirements for its use and disposal in the United States, including documentation and handling procedures to ensure safety and compliance.

Are there alternatives to sparsentan (CAS: 254740-64-2) in synthesis?

Several alternatives to sparsentan (CAS: 254740-64-2) exist in synthesis, including angiotensin II receptor antagonists and dual angiotensin receptor blockers. These alternatives, such as losartan and valsartan, offer similar therapeutic effects and can be used as substitutes depending on the specific requirements and availability.

What is the market or research trend for sparsentan (CAS: 254740-64-2)?

The market for sparsentan (CAS: 254740-64-2) is growing due to its potential in treating hypertension and kidney disease. Research trends are focusing on its efficacy and safety, as well as exploring its use in combination therapies. Additionally, there is increasing interest in its development for other therapeutic areas, driven by clinical trial results and positive market responses.

How should waste containing sparsentan (CAS: 254740-64-2) be handled?

Waste containing sparsentan (CAS: 254740-64-2) should be managed according to local and national regulations. Collection and disposal should be done through authorized waste management facilities. Incineration or professional waste disposal is recommended to ensure the safe removal of hazardous materials. Proper handling and storage are crucial to prevent environmental contamination and ensure worker safety.