PROTAC SGK3 degrader-1

Basic Information

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CAS Number

2381320-35-8

Molecular Formula

C57H73FN10O11S2

Molecular Weight

1157.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC(C)(C)[C@H](NC(=O)COCCOCCOCCCCCCN1C[C@H](COC2=NC(=NC3NN=CC2=3)C2C=CC(=CC=2)NS(=O)(=O)C2C=C(C)C=CC=2F)OCC1)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1C=CC(=CC=1)C1SC=NC=1C

InChI

InChI=1S/C57H73FN10O11S2/c1-37-10-19-46(58)48(28-37)81(73,74)66-42-17-15-41(16-18-42)52-63-53-45(31-61-65-53)55(64-52)79-34-44-33-67(21-23-78-44)20-8-6-7-9-22-75-24-25-76-26-27-77-35-49(70)62-51(57(3,4)5)56(72)68-32-43(69)29-47(68)54(71)59-30-39-11-13-40(14-12-39)50-38(2)60-36-80-50/h10-19,28,31,36,43-44,47,51,66,69H,6-9,20-27,29-30,32-35H2,1-5H3,(H,59,71)(H,62,70)(H,61,63,64,65)/t43-,44-,47+,51-/m1/s1

InChIKey

RTFQFPZKDYMMMJ-RIAKQDHQSA-N

LogP

6.19904000000001

Topological Polar Surface Area

261.65 Å²

Hydrogen Bond Donor/Acceptor

5 / 21

Complexity

2050

Synonyms & References

English

PROTAC SGK3 degrader-1
SGK3 degrader-1

FAQ

What regulatory guidelines apply to PROTAC SGK3 degrader-1 (CAS: 2381320-35-8)?

PROTAC SGK3 degrader-1 (CAS: 2381320-35-8) is subject to regulatory guidelines such as the REACH regulations in the European Union, ensuring that it meets the necessary safety and environmental standards. It is also important to comply with FDA and EPA requirements for the handling and manufacturing of chemical compounds. Additionally, GHS classification provides a standardized approach for the classification and labeling of chemicals, which should be followed to ensure safety in handling, storage, and transportation.

Are there alternatives to PROTAC SGK3 degrader-1 in synthesis (CAS: 2381320-35-8)?

There are several alternatives to PROTAC SGK3 degrader-1 in synthesis. Researchers may consider using isomers or analogs such as PROTAC SGK3 degrader-2 or other variants to achieve similar or improved results. Common alternative reagents might include different linkers or modifiers that could enhance the degradation pathway. These alternatives may offer variations in potency, selectivity, and stability, allowing for tailored applications in drug discovery and development.

What is the market or research trend for PROTAC SGK3 degrader-1 (CAS: 2381320-35-8)?

The market and research trends for PROTAC SGK3 degrader-1 (CAS: 2381320-35-8) are centered around its potential in targeted protein degradation. As a degrader, it is being explored for its role in treating diseases such as cancer and neurodegenerative disorders. Market demand is growing as more pharmaceutical companies and research institutions focus on developing PROTAC-based therapies. Additionally, emerging trends include the integration of PROTACs with existing drugs to enhance their therapeutic effects and reduce side effects.

How should waste containing PROTAC SGK3 degrader-1 (CAS: 2381320-35-8) be handled?

Waste containing PROTAC SGK3 degrader-1 (CAS: 2381320-35-8) should be handled with care to ensure safety and environmental protection. Collect waste liquids in appropriate containers and store them separately from other hazardous materials. For solid waste, follow local regulations for disposal. Incineration is a common method for waste disposal, ensuring that the waste is properly managed and does not pose a risk to the environment. Always consult with a professional waste management service to ensure compliance with all regulations and safety protocols.