1,3-Thiazolidine-2,4-dione

Basic Information

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CAS Number

2295-31-0

Molecular Formula

C3H3NO2S

Molecular Weight

117.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

125-127 °C

Boiling Point

305.7°C at 760 mmHg

Water Solubility

Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether.

Flash Point

178-179℃/19mm

Refractive Index

1.5130 (estimate)

SMILES

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O=C(N1)SCC1=O

InChI

InChI=1S/C3H3NO2S/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6)

InChIKey

ZOBPZXTWZATXDG-UHFFFAOYSA-N

LogP

-0.03059999999999996

Topological Polar Surface Area

46.17 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

122

Safety Information

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Hazard Statement

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2,4-Thiazolidinedione
TZD
TIMTEC-BB SBB000047
THIAZOLIDINE-2,4-DIONE
2,4(3H,5H)-Thiazoledione
2,4-Dioxothiazolidine
Thiazolidinedione
Thiazolidinedione-2,4
1,3-Thiazolidine-2,4-dione
2,4-Thiazolidinedion
2.4-Thiazolidinedione
thiazolidin-2,4-dione
2,4-Thiazolidindione
2,4-thiazolidinone
2,4-Thiazolinedione
2-thiazolidin-4-one
usafek-5496
2,4-噻唑烷二酮
Thiazolidindione
2,4-thiazolidine dione
AA68LXK93C
NSC6745
C3H3NO2S
thiazolidine-dione
2,4thiazolidinedione
2,4 thiazolidinedione
2,5H)-Thiazoledione
PubChem17
Thiazolidine-2,4-dione

MDL Number

MFCD00005478

Customs Code

2942000000

FAQ

What is 1,3-Thiazolidine-2,4-dione (CAS: 2295-31-0)?

1,3-Thiazolidine-2,4-dione (CAS: 2295-31-0) is a heterocyclic compound with the chemical formula C3H3NS2O2. It features a five-membered thiazolidine ring containing sulfur and nitrogen atoms, with two carbonyl groups at positions 2 and 4. This compound is known for its white crystalline appearance, solubility in polar solvents, and stability under controlled conditions. It serves as a key intermediate in organic synthesis and pharmaceutical applications.

What are the main uses of 1,3-Thiazolidine-2,4-dione (CAS: 2295-31-0)?

1,3-Thiazolidine-2,4-dione (CAS: 2295-31-0) is widely used in pharmaceuticals as a precursor for drugs like Metformin, which treats diabetes. It also finds applications in industrial chemistry for synthesizing other compounds, in research for studying metabolic processes, and in food additives as a stabilizer. Its versatility makes it relevant in drug development and chemical manufacturing.

Is 1,3-Thiazolidine-2,4-dione (CAS: 2295-31-0) safe?

1,3-Thiazolidine-2,4-dione (CAS: 2295-31-0) is considered moderately toxic; prolonged exposure may cause skin or eye irritation. Safety precautions include wearing protective gloves, goggles, and ensuring proper ventilation during handling. It is not classified as a carcinogen, but adherence to OSHA and EPA guidelines is recommended to minimize health risks.

How should 1,3-Thiazolidine-2,4-dione (CAS: 2295-31-0) be stored?

1,3-Thiazolidine-2,4-dione (CAS: 2295-31-0) should be stored in airtight, moisture-proof containers at temperatures below 25°C. It is sensitive to light, so storage in a dark, cool environment is essential. Avoid exposure to incompatible substances and maintain low humidity to ensure stability and prolong shelf life.