(11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl isonicotinate | CAS No. 2265-64-7

(11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl isonicotinate

Basic Information

CAS Number

2265-64-7

Molecular Formula

C28H32FNO6

Molecular Weight

497.56 g/mol

AD

Basic Physical Properties

Melting Point

256°C

CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COC(=O)C5=CC=NC=C5)O)C)O)F)C

InChI

InChI=1S/C28H32FNO6/c1-16-12-21-20-5-4-18-13-19(31)6-9-25(18,2)27(20,29)22(32)14-26(21,3)28(16,35)23(33)15-36-24(34)17-7-10-30-11-8-17/h6-11,13,16,20-22,32,35H,4-5,12,14-15H2,1-3H3/t16-,20+,21+,22+,25+,26+,27+,28+/m1/s1

InChIKey

BQTXJHAJMDGOFI-NJLPOHDGSA-N

LogP

3.155400000000002

Topological Polar Surface Area

113.79 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

1040

Synonyms & References

English

  • Voren [veterinary] (TN)
  • 5-tert-butyl 1-ethyl 3-amino-6,6-diethylpyrrolo[3,4-c]pyrazole-1,5(4H,6H)-dicarboxylate
  • [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-luoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] pyridine-4-carboxylate
  • NCGC00249903-01
  • [2-[(8S, 9R, 10S, 11S, 13S, 14S, 16R, 17R)-9-fluoro-11, 17-dihydroxy-10, 13, 16-trimethyl-3-oxo-6, 7, 8, 11, 12, 14, 15, 16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] pyridine-4-carboxylate
  • 8LGC0BOA71
  • Dexamethasone 21-isonicotinate
  • [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] pyridine-4-carboxylate
  • 2265-64-7
  • UNII-8LGC0BOA71
  • Tox21_113679
  • D07797
  • PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11,17-DIHYDROXY-16-METHYL-21-((4-PYRIDINYLCARBONYL)OXY)-,(11.BETA.,16.ALPHA.)-
  • Auxilson
  • CAS-2265-64-7
  • DB11487
  • EINECS 218-866-5
  • Pyridin-4-carbonsaeure-(dexamethason-21')-ester [German]
  • CHEMBL3186453
  • AUXISONE
  • DEXAMETHASONE ISONICOTINATE [MART.]
  • DEXAMETHASONE ISONICOTINATE
  • DEXAMETHASONE 21-ISONICOTINATE [MI]
  • NS00008313
  • SCHEMBL7811
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-alpha-methyl-, 21-isonicotinate
  • dexamethasone-21-isonicotinate
  • DEXAMETHASONE ISONICOTINATE [WHO-DD]
  • DTXSID3057690
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-((4-pyridinylcarbonyl)oxy)-, (11beta,16alpha)-
  • DEXAMETHASONE ISONICOTINATE [EP IMPURITY]

MDL Number

MFCD01317548

FAQ

What is (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl isonicotinate (CAS: 2265-64-7)?

This compound is a steroidal derivative with a fluorine atom attached to the 9th carbon and a carboxylic acid group at the 21st carbon, conjugated with an isonicotinic acid moiety. It is a complex steroid structure with both hormonal and non-hormonal pharmacological activities.

What are the main uses of (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl isonicotinate (CAS: 2265-64-7)?

This compound is primarily used in pharmaceutical research for its hormonal and non-hormonal effects. It may serve as a starting material or intermediate in the synthesis of other steroidal compounds with potential therapeutic applications.

Is (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl isonicotinate (CAS: 2265-64-7) safe?

The safety of this compound depends on the intended use and the route of administration. It should be handled with caution and under the guidance of a qualified professional. Proper personal protective equipment, such as gloves and safety goggles, is recommended during handling to prevent direct contact with skin or inhalation of aerosols.

How should (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl isonicotinate (CAS: 2265-64-7) be stored?

Store this compound in a tightly sealed container at room temperature, away from direct sunlight and moisture. It should be kept in a cool, dry environment and protected from light to prevent degradation. Avoid storing it in high humidity areas to maintain its stability and potency.

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