9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine | CAS No. 226415-08-3

9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine

Basic Information

CAS Number

226415-08-3

Molecular Formula

C38H34FN5O6

Molecular Weight

675.72 g/mol

AD

Basic Physical Properties

O=C(NC1=C2N=CN([C@@H]3O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@@H](O)[C@@H]3F)C2=NC=N1)C7=CC=CC=C7

InChI

InChI=1S/C38H34FN5O6/c1-47-28-17-13-26(14-18-28)38(25-11-7-4-8-12-25,27-15-19-29(48-2)20-16-27)49-21-30-33(45)31(39)37(50-30)44-23-42-32-34(40-22-41-35(32)44)43-36(46)24-9-5-3-6-10-24/h3-20,22-23,30-31,33,37,45H,21H2,1-2H3,(H,40,41,43,46)/t30-,31+,33-,37-/m1/s1

InChIKey

DDOOVEXTSRBCMU-MHHBZGPPSA-N

LogP

5.700900000000006

Topological Polar Surface Area

129.85000000000002 Ų

Hydrogen Bond Donor/Acceptor

2 / 11

Complexity

1060

Synonyms & References

English

  • 9-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-2-fluoro-β-D-arabinofuranosyl]-N6 -benzoyladenine
  • DMT-2'-F-Bz-dA
  • N-(9-((2R,3S,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
  • N-[9-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]purin-6-yl]benzamide
  • N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]purin-6-yl]benzamide
  • N-[9-[5-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]purin-6-yl]benzam
  • N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine

MDL Number

MFCD15145200

FAQ

What regulatory guidelines apply to 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine (CAS: 226415-08-3)?

The compound 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine is subject to various regulatory guidelines such as GHS classification for hazardous materials, REACH regulations for EU markets, and FDA/EPA requirements for pharmaceutical and environmental safety. Specific handling, storage, and disposal must comply with local and international regulations.

Are there alternatives to 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine in synthesis?

Alternatives to 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine include related nucleosides like 5-fluoro-2′-deoxyuridine and other modified purines. These alternatives vary in reactivity and can serve as useful analogs in medicinal chemistry and pharmaceutical research.

What is the market or research trend for 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine (CAS: 226415-08-3)?

The market and research trends for 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine show increasing interest in its potential use as an anticancer agent. Studies are focusing on its efficacy, bioavailability, and toxicity, with ongoing research aiming to improve its therapeutic profile.

How should waste containing 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine (CAS: 226415-08-3) be handled?

Waste containing 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine should be collected in a sealed container and disposed of through incineration or professional waste disposal services. Proper environmental protection precautions, including the use of appropriate personal protective equipment, must be followed to ensure safety and compliance with regulatory standards.

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