2-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one | CAS No. 224788-34-5

2-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one

Basic Information

CAS Number

224788-34-5

Molecular Formula

C22H29N5O4S

Molecular Weight

459.57 g/mol

AD

Basic Physical Properties

Melting Point

81-83°C

CCCc1nc(c2n1[nH]c(nc2=O)c1cc(ccc1OCC)S(=O)(=O)N1CCCCC1)C

InChI

InChI=1S/C22H29N5O4S/c1-4-9-19-23-15(3)20-22(28)24-21(25-27(19)20)17-14-16(10-11-18(17)31-5-2)32(29,30)26-12-7-6-8-13-26/h10-11,14H,4-9,12-13H2,1-3H3,(H,24,25,28)

InChIKey

QAYHPAMSDMZXJB-UHFFFAOYSA-N

LogP

2.918820000000001

Topological Polar Surface Area

109.65999999999998 Ų

Hydrogen Bond Donor/Acceptor

1 / 9

Synonyms & References

English

  • Pseudo Vardenafil
  • 2-(2-ethoxy-5-piperidin-1-ylsulfonylphenyl)-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one
  • Vardenafil
  • Piperadino vardenafil
  • Piperidenafil
  • Piperidino-vardenafil
  • seudo Vardenafil
  • 2-(2-ethoxy-5-(piperidin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one

MDL Number

MFCD09752153

FAQ

What regulatory guidelines apply to 2-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224788-34-5)?

2-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224788-34-5) must comply with the GHS (Globally Harmonized System of Classification and Labelling of Chemicals) for classification and labeling. It should also adhere to REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) regulations in the European Union. In the United States, FDA and EPA have specific requirements for the handling and disposal of potentially hazardous chemicals.

Are there alternatives to 2-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224788-34-5) in synthesis?

Several alternatives can be used in the synthesis of 2-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224788-34-5), including 2-ethyl-5-(1-piperidinylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one and other related imidazole compounds with similar structures and properties. Alternative reagents such as different coupling agents and solvents may also be considered depending on the specific reaction conditions.

What is the market or research trend for 2-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224788-34-5)?

The market and research trends for 2-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224788-34-5) are focused on its potential applications in pharmaceuticals, particularly as an intermediate in the synthesis of other active pharmaceutical ingredients. Research is also exploring its use in agricultural chemicals and as a potential anti-inflammatory agent. Market demand is driven by increasing interest in novel chemical entities with unique biological properties.

How should waste containing 2-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224788-34-5) be handled?

Waste containing 2-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224788-34-5) should be collected in appropriate containers and stored in a secure, well-ventilated area. It should then be disposed of through professional waste disposal services that specialize in hazardous waste. Environmental precautions include proper labeling, spill containment, and adherence to local, national, and international regulations regarding the disposal of toxic substances.

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