2-Hydroxy-4-methoxybenzoic acid

Basic Information

View in Editor

CAS Number

2237-36-7

Molecular Formula

C8H8O4

Molecular Weight

168.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

158.0 to 162.0 deg-C

Boiling Point

328.7℃ at 760 mmHg

Flash Point

137.9℃

Solubility

,Ethyl Acetate

Refractive Index

1.4611 (estimate)

SMILES

View in Editor

COC1=CC(=C(C=C1)C(=O)O)O

InChI

InChI=1S/C8H8O4/c1-12-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1H3,(H,10,11)

InChIKey

MRIXVKKOHPQOFK-UHFFFAOYSA-N

LogP

1.099

Topological Polar Surface Area

66.75999999999999 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

168

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Storage Conditions

2-8℃

Synonyms & References

English

CHEBI:167809
Z104499836
HMS2269N04
s5160
2-hydroxy-4-methoxy-benzoic acid
SY008083
AC-11620
MFCD00002450
AMY18271
NS00014744
FT-0618866
AC-34348
NCIOpen2_001552
2-Hydroxy-4-methoxybenzoic acid
2-Hydroxy-4-methoxybenzoicacid
NSC 94304
2-Hydroxy-p-anisic Acid
EINECS 218-801-0
CHEMBL507095
NSC-94304
2237-36-7
4-methoxy-2-hydroxobenzoic acid
AKOS000120626
NCGC00246993-01
EN300-21485
MLS000517276
PS-3720
SMR000127395
W-107479
MRIXVKKOHPQOFK-UHFFFAOYSA-N
Benzoic acid, 2-hydroxy-4-methoxy-

MDL Number

MFCD00002450

Customs Code

2942000000

FAQ

What is 2-Hydroxy-4-methoxybenzoic acid (CAS: 2237-36-7)?

2-Hydroxy-4-methoxybenzoic acid (CAS: 2237-36-7) is an aromatic carboxylic acid with the chemical formula C8H8O4. It contains hydroxyl and methoxy functional groups, making it a versatile compound in organic chemistry. Known for its mild acidity and solubility in polar solvents, it is a white crystalline solid with a characteristic aromatic odor. This compound is commonly used as an intermediate in pharmaceutical and industrial applications.

What are the main uses of 2-Hydroxy-4-methoxybenzoic acid (CAS: 2237-36-7)?

2-Hydroxy-4-methoxybenzoic acid (CAS: 2237-36-7) is widely utilized in pharmaceuticals as a precursor for drugs like antihistamines and analgesics. It also serves in the fragrance industry for flavoring agents and in polymer chemistry for synthetic materials. Additionally, it is employed in food preservation and research as a building block for further chemical modifications. Its unique structure makes it valuable in developing functional compounds for diverse applications.

Is 2-Hydroxy-4-methoxybenzoic acid (CAS: 2237-36-7) safe?

2-Hydroxy-4-methoxybenzoic acid (CAS: 2237-36-7) is generally considered safe when handled properly, with low acute toxicity in standard exposure scenarios. However, it may cause mild skin or eye irritation. Safety guidelines recommend using appropriate protective equipment, such as gloves and safety goggles, and ensuring proper ventilation during handling. Adherence to OSHA and EPA standards is advised to ensure safe usage in industrial and research settings.

How should 2-Hydroxy-4-methoxybenzoic acid (CAS: 2237-36-7) be stored?

2-Hydroxy-4-methoxybenzoic acid (CAS: 2237-36-7) should be stored in a sealed, airtight container in a cool, dry place (ideally 2-8°C) to maintain stability. Protection from light and moisture is essential to prevent degradation. Store in a well-ventilated area, away from incompatible substances, and ensure proper labeling to comply with chemical storage safety standards.