Methyl 2-amino-3-methylbenzoate

Basic Information

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CAS Number

22223-49-0

Molecular Formula

C9H11NO2

Molecular Weight

165.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

115-117 ºC

Boiling Point

153°C/23mmHg

Density

1.132

Flash Point

131.1℃

Refractive Index

1.558

SMILES

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CC1=C(C(=CC=C1)C(=O)OC)N

InChI

InChI=1S/C9H11NO2/c1-6-4-3-5-7(8(6)10)9(11)12-2/h3-5H,10H2,1-2H3

InChIKey

VSFYTPXXMLJNAU-UHFFFAOYSA-N

LogP

1.3638199999999998

Topological Polar Surface Area

52.32 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

170

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-methyl-6-methoxycarbonylaniline
EINECS 244-847-6
2-Amino-3-methylbenzoic Acid Methyl Ester
Methyl 2-amino-3-methylbenzoate
SB75807
SCHEMBL228051
BENZOIC ACID, 2-AMINO-3-METHYL-, METHYL ESTER
11X-0097
A4774
Methyl 2-amino-3-methylbenzenecarboxylate
FT-0638199
2-Amino-3-methyl-benzoic acid methyl ester
Methyl 3-methylanthranilate
DTXSID50176764
2-Amino-3-methylbenzoesauremethylester
EN300-43096
2-Amino-m-toluic Acid Methyl Ester
MFCD06200918
Methyl 2-Amino-m-toluate
W-206741
22223-49-0
AC-6160
AM20030374
PB29358
SY017216
Methyl2-amino-3-methylbenzoate
CS-W020651
3-Methylanthranilic Acid Methyl Ester
BCP24530
M2193
NS00027104

MDL Number

MFCD06200918

Customs Code

2922499990

FAQ

What are the physical and chemical properties of Methyl 2-amino-3-methylbenzoate (CAS: 22223-49-0)?

Methyl 2-amino-3-methylbenzoate (CAS: 22223-49-0) is a crystalline compound with a molecular weight of approximately 178.22 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is less reactive compared to other aromatic amines but can undergo typical amine reactions like nitration and sulfonation under appropriate conditions.

How is Methyl 2-amino-3-methylbenzoate (CAS: 22223-49-0) typically synthesized?

Methyl 2-amino-3-methylbenzoate is typically synthesized by reacting methyl benzoate with ammonia in the presence of a catalyst such as Raney nickel. The reaction proceeds under mild conditions, yielding a high selectivity and yield. The process is optimized for efficient production and safety.

What industries use Methyl 2-amino-3-methylbenzoate (CAS: 22223-49-0)?

Methyl 2-amino-3-methylbenzoate (CAS: 22223-49-0) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It also finds applications in the polymer industry for enhancing properties of polymers and in the development of sensors and semiconductors for electronic devices.

What precautions should be taken when handling Methyl 2-amino-3-methylbenzoate (CAS: 22223-49-0)?

When handling Methyl 2-amino-3-methylbenzoate (CAS: 22223-49-0), it is important to wear personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be contained and cleaned up using appropriate methods, and safety data sheets (SDS) should be consulted for detailed handling instructions.