2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one

Basic Information

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CAS Number

22150-76-1

Molecular Formula

C9H11N5O3

Molecular Weight

237.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

>210°C dec.

Boiling Point

379.74°C (rough estimate)

Flash Point

310.7 °C

Solubility

Bioptein is very slightly soluble in water. The solubility of biopterin is about 0.01 g per 100 g of water (220C). Concentrated solutions of biopterin may be prepared using 0.05M NaOH. Ultrasonication may be used to improve dissolution.

Refractive Index

1.7610 (estimate)

Specific Rotation

D24 -50° (c = 0.4 in 0.1N HCl); D24 -26° (c = 0.92 in 0.1N NaOH)

SMILES

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CC(C(C1=CN=C2C(=N1)C(=O)NC(=N2)N)O)O

InChI

InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h2-3,6,15-16H,1H3,(H3,10,11,13,14,17)/t3-,6-/m0/s1

InChIKey

LHQIJBMDNUYRAM-DZSWIPIPSA-N

LogP

-1.2905000000000009

Topological Polar Surface Area

138.01 Å²

Hydrogen Bond Donor/Acceptor

5 / 8

Complexity

348

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

MFCD00036787
SCHEMBL18662632
BIOPTERIN [MI]
L-Erythro-Biopterin
22150-76-1
Pterin H B2
6-(L-erythro-1,2-dihydroxypropyl)-pterin
EINECS 244-807-8
L-Biopterin
Q408256
s5577
AKOS030254292
2-amino-6-((1R,2S)-1,2-dihydroxypropyl)pteridin-4(3H)-one
2-amino-6-((1R,2S)-1,2-dihydroxypropyl)pteridin-4(1H)-one
EN300-7365623
AKOS025312532
9036-22-0
CHEBI:63931
4(1H)-Pteridinone, 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-
(S-(R*,S*))-2-Amino-6-(1,2-dihydroxypropyl)-1H-pteridin-4-one
CS-6962
4(3H)-Pteridinone, 2-amino-6-(L-erythro-1,2-dihydroxypropyl)-
Z3245415986
(1R,2S)-1-(2-AMINO-4-HYDROXYPTERIDIN-6-YL)PROPANE-1,2-DIOL
4(1H)-Pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-, (S-(R*,S*))-
BCP04171
DTXSID30912041
(L-erythro)-2-Amino-6-(1,2-dihydroxypropyl)-4(3H)-pteridinon
2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3H-pteridin-4-one
SCHEMBL258466
NSC-339699

MDL Number

MFCD00036787

Customs Code

2933990090

FAQ

What is 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one (CAS: 22150-76-1)?

2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one (CAS: 22150-76-1) is a chemical compound that serves as a key intermediate in the synthesis of other pteridine derivatives. It is used in pharmaceutical research and development, particularly in the production of folate analogs and other biologically active compounds.

What are the main uses of 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one (CAS: 22150-76-1)?

2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one (CAS: 22150-76-1) is primarily used in the pharmaceutical industry as an intermediate for synthesizing various folate analogs. It also finds applications in research for studying pteridine metabolism and in the development of new therapeutic agents.

Is 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one (CAS: 22150-76-1) safe?

2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one (CAS: 22150-76-1) is generally safe when used under proper conditions. However, it is essential to handle it with care to avoid skin contact and inhalation of dust. Protective gloves and goggles are recommended during handling. Storage in a cool, dry place away from direct sunlight is advised.

How should 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one (CAS: 22150-76-1) be stored?

2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one (CAS: 22150-76-1) should be stored in a cool, dry place away from direct sunlight and heat sources to maintain its stability. It should be kept in a tightly sealed container to prevent moisture absorption. Refrigeration is not typically necessary but can be used if the storage temperature is maintained below 25°C (77°F).