3-Bromo-2-pyrazinamine

Basic Information

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CAS Number

21943-12-4

Molecular Formula

C4H4BrN3

Molecular Weight

174 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

275.6°C at 760 mmHg

Flash Point

120.481℃

SMILES

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C1=CN=C(C(=N1)N)Br

InChI

InChI=1S/C4H4BrN3/c5-3-4(6)8-2-1-7-3/h1-2H,(H2,6,8)

InChIKey

BFEUGUAUYFATRV-UHFFFAOYSA-N

LogP

0.8212999999999999

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

77.7

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

EN300-110283
FS-2747
SY017457
FT-0646811
DTXSID40563422
MB08183
Ethyl5-methyl-3-(methylthio)-4,4-dioxo-4,5-dihydro-4lambda6-benzo[c]thieno[3,4-e][1,2]thiazine-1-carboxylate
Bromopyrazin-2-amine
CS-W008796
3-bromopyrazin-2-amine
3-bromo-pyrazin-2-ylamine
BCP23405
AM20070326
AKOS005259030
SCHEMBL557517
C4H4BrN3
A4698
2-Amino-3-bromopyrazine
Q-103302
CHEMBL4515428
21943-12-4
3-BROMO-2-PYRAZINAMINE
MFCD09909692
AC-5179
BFEUGUAUYFATRV-UHFFFAOYSA-N
3-Bromo-2-pyrazinamine
2-Pyrazinamine, 3-bromo-
2-AMINO-3-BROMO-PYRAZINE
2-Amino-3-brom-pyrazin
3-Bromo-pyrazinamine
3-bromo-pyrazine-2-amine

MDL Number

MFCD09909692

Customs Code

2933990090

FAQ

What regulatory guidelines apply to 3-Bromo-2-pyrazinamine (CAS: 21943-12-4)?

3-Bromo-2-pyrazinamine (CAS: 21943-12-4) falls under the scope of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), which includes classification for health hazards, environmental hazards, and flammability. Additionally, it is regulated by the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) in the European Union, requiring manufacturers and importers to register substances above a certain tonnage threshold. In the United States, it must comply with the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) for safety and regulatory compliance.

Are there alternatives to 3-Bromo-2-pyrazinamine (CAS: 21943-12-4) in synthesis?

In the synthesis of 3-Bromo-2-pyrazinamine (CAS: 21943-12-4), alternative reagents such as 3-chloro-2-pyrazinamine or 2-chloro-3-pyrazinamine can be used as bromine analogs. Other common alternatives include various pyrimidines and imidazoles, which can serve similar functional groups. These alternatives are often chosen based on availability, cost, and specific reaction conditions.

What is the market or research trend for 3-Bromo-2-pyrazinamine (CAS: 21943-12-4)?

The market for 3-Bromo-2-pyrazinamine (CAS: 21943-12-4) is primarily driven by its use in pharmaceuticals and research applications. Recent trends indicate a growing interest in its use as an intermediate in the synthesis of anti-inflammatory and antimicrobial agents. Research is also exploring its potential in cancer treatment. Market trends suggest a steady demand, with increasing emphasis on sustainable and environmentally friendly synthesis methods.

How should waste containing 3-Bromo-2-pyrazinamine (CAS: 21943-12-4) be handled?

Waste containing 3-Bromo-2-pyrazinamine (CAS: 21943-12-4) should be collected in appropriate, leak-proof containers and stored away from heat and ignition sources. For disposal, it is recommended to consult the Material Safety Data Sheet (MSDS) and local regulations. Common disposal methods include incineration or professional waste disposal services that comply with environmental protection laws. Proper training and personal protective equipment (PPE) should be used during handling and disposal to ensure safety.