4-Pyridazinamine

Basic Information

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CAS Number

20744-39-2

Molecular Formula

C4H5N3

Molecular Weight

95.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

127-133 °C

Boiling Point

326.2°C at 760 mmHg

Density

1.216

Flash Point

177.3℃

Refractive Index

1.598

SMILES

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C1=CN=NC=C1N

InChI

InChI=1S/C4H5N3/c5-4-1-2-6-7-3-4/h1-3H,(H2,5,6)

InChIKey

LUCGBEPEAUHERV-UHFFFAOYSA-N

LogP

0.05880000000000002

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

54.9

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Sensitiveness

sensitive to heat

Synonyms & References

English

MFCD00233975
W-206553
UNII-2H2SSX4YHL
pyridazine-4-amine
Pyridazine, 4-amino-
DTXSID90305399
BCP27543
4-aminopyridazine
NSC170657
2H2SSX4YHL
4-Aminopyridazine, AldrichCPR
pyridazin-4-ylamine
AM20090167
PS-9354
NSC-170657
4-Aminopyridazine, 97%
FT-0617605
CS-W007757
EN300-72823
pyridazin-4-amine
PB29051
SY008183
AKOS005256693
AC-23844
pyridazin-4-yl-amine
4-Pyridazinamine
20744-39-2
A4503
4-Aminopyridazine
4-Chloro-pyridazine hydrochloride
N-1-Boc-2-ethyl-piperazine

MDL Number

MFCD00233975

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 4-Pyridazinamine (CAS: 20744-39-2)?

4-Pyridazinamine (CAS: 20744-39-2) is a crystalline solid with a molecular weight of approximately 115.13 g/mol. It is slightly soluble in water and has a pKa of approximately 8.5. This compound is mildly reactive, particularly with strong acids and bases. Its solubility in organic solvents like methanol and ethanol is good to moderate.

How is 4-Pyridazinamine (CAS: 20744-39-2) typically synthesized?

4-Pyridazinamine (CAS: 20744-39-2) is commonly synthesized by the reduction of 4-pyridazinecarboxylic acid using a reducing agent such as sodium borohydride. This process provides good yield and selectivity, typically ranging from 75% to 90%, depending on the purity of the starting material and reaction conditions.

What industries use 4-Pyridazinamine (CAS: 20744-39-2)?

4-Pyridazinamine (CAS: 20744-39-2) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the development of sensors, where its reactivity with various analytes makes it useful for detection purposes. Additionally, it is explored in the polymer industry for the preparation of specific polymers with unique properties.

What precautions should be taken when handling 4-Pyridazinamine (CAS: 20744-39-2)?

When handling 4-Pyridazinamine (CAS: 20744-39-2), it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be immediately neutralized with an appropriate acid or base, followed by thorough cleaning. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.