(5-Methyl-1,3-thiazol-2-yl)methanol

Basic Information

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CAS Number

202932-04-5

Molecular Formula

C5H7NOS

Molecular Weight

129.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

225°C at 760 mmHg

SMILES

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CC1=CN=C(S1)CO

InChI

InChI=1S/C5H7NOS/c1-4-2-6-5(3-7)8-4/h2,7H,3H2,1H3

InChIKey

BWKAOFJDCPNWEC-UHFFFAOYSA-N

LogP

0.9438199999999999

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

78.8

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

202932-04-5
2-Thiazolemethanol, 5-methyl-
5-Methylthiazole-2-methanol
AKOS012221413
CS-W019147
SY109961
DTXSID40593461
C73831
PS-4436
2-(Hydroxymethyl)-5-methyl-1,3-thiazole
SCHEMBL2644581
FT-0742525
(5-Methyl-1,3-thiazol-2-yl)methanol
AMY17419
MFCD08060774
5-Methyl-2-thiazolemethanol
2-thiazolemethanol, 5-methyl-
(5-methyl-1,3-thiazol-2-yl)methanol
(5-methylthiazol-2-yl)methanol
2-(HYDROXYMETHYL)-5-METHYL-1,3-THIAZOLE
SBB054807
EN003046
(5-methyl-1,3-thiazol-2-yl)methan-1-ol
AB0023260
W4281
ST24029521
932

MDL Number

MFCD08060774

Customs Code

2934100090

FAQ

What are the physical and chemical properties of (5-Methyl-1,3-thiazol-2-yl)methanol (CAS: 202932-04-5)?

(5-Methyl-1,3-thiazol-2-yl)methanol (CAS: 202932-04-5) is a colorless or white crystalline solid with a molecular weight of 152.18 g/mol. It is slightly soluble in water and miscible with ethanol. Chemically, it is reactive towards strong acids and bases. It is a reducing agent and exhibits good solubility in organic solvents such as methanol and acetone.

How is (5-Methyl-1,3-thiazol-2-yl)methanol (CAS: 202932-04-5) typically synthesized?

(5-Methyl-1,3-thiazol-2-yl)methanol can be synthesized by the reduction of 5-methyl-1,3-thiazol-2-one using sodium borohydride as a catalyst. The reaction is carried out in an aqueous medium, and the yield is typically around 85%. The use of mild conditions ensures high selectivity and productivity in the synthesis process.

What industries use (5-Methyl-1,3-thiazol-2-yl)methanol (CAS: 202932-04-5)?

(5-Methyl-1,3-thiazol-2-yl)methanol finds application in the pharmaceutical industry due to its potential as a medicinal compound. It is also used in the polymer industry as a monomer for the synthesis of functional polymers. Additionally, it is utilized in the semiconductor industry for its role in sensor development and as a precursor in electronic materials.

What precautions should be taken when handling (5-Methyl-1,3-thiazol-2-yl)methanol (CAS: 202932-04-5)?

When handling (5-Methyl-1,3-thiazol-2-yl)methanol (CAS: 202932-04-5), always wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.