4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid

Basic Information

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CAS Number

1918-02-1

Molecular Formula

C6H3Cl3N2O2

Molecular Weight

241.46 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

219°C(dec.)

Boiling Point

420.5 ℃ at 760 mmHg

Water Solubility

420 mg/L

Flash Point

>110℃(230℉)(lit.)

Solubility

Soluble in acetone

Refractive Index

1.6770 (estimate)

SMILES

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Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl

InChI

InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)

InChIKey

NQQVFXUMIDALNH-UHFFFAOYSA-N

LogP

2.3222

pKa

4.1(at 25℃)

Topological Polar Surface Area

76.21 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

216

Safety Information

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GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 9 Class 9

Toxicity

LD50 in rats, mice, rabbits, guinea pig, chickens, sheep, cattle (mg/kg): 8200, 2000-4000, 2000, 3000, 6000, >1000, >750 orally (Mullison)

Synonyms & References

English

4-Amino-3,5,6-trichloropicolinic acid
picloram plant cell culture tested
4-amino-3,5,6-trichloropyridine-2-carboxylic acid
RARECHEM AL BO 1809
PICLORAM
TIMTEC-BB SBB000816
TORDON
TORDON(R)
3,5,6-Trichloro-4-Aminopicolinic acid
3,5,6-trichloro-4-aminopyridine-2-carboxylic acid
2-Pyridinemethanol,4-amino-3,5,6-trichloro
3,5,6-trichloro-4-amino-picolinic acid
4-Amino-3,5,6-trichlor-2-pyridinmethanol
4-amino-3,5,6-trichloro-2-pyridinecarboxylic acid
4-Amino-3,5,6-trichloropicolinic ac
4-Amino-3,5,6-trichloropicolinic acid,4-Amino-3,5,6-trichloropyridine-2-carboxylic acid,Picloram
ATCP
Amdon
k-Pin
Grazon
TORDAN
Borolin
Chloramp
2-Pyridinecarboxylic acid, 4-amino-3,5,6-trichloro-
Tordon 22K
Tordon 10K
Tordon 101 mixture
Amdon grazon
4-Aminotrichloropicolinic acid
Piclorame
Picolinic acid, 4-amino-3,5,6-trichloro-

MDL Number

MFCD00012101

FAQ

What is 4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid (CAS: 1918-02-1)?

4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid (CAS: 1918-02-1) is a chlorinated pyridinecarboxylic acid derivative with the chemical formula C6H4Cl3NO2. It is a white crystalline solid, commonly used as an intermediate in chemical synthesis. The compound exhibits moderate solubility in polar solvents and is characterized by its aromatic ring structure with three chlorine atoms and an amino group attached.

What are the main uses of 4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid (CAS: 1918-02-1)?

4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid (CAS: 1918-02-1) is primarily used in pharmaceutical research for synthesizing antifungal and antibacterial agents. It also serves as an industrial chemical in the production of dyes and pesticides. In research settings, it acts as a key building block for organic compounds. Its applications span across drug development, chemical manufacturing, and scientific studies due to its versatile functional groups.

Is 4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid (CAS: 1918-02-1) safe?

4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid (CAS: 1918-02-1) requires careful handling due to potential toxicity. It may cause skin and eye irritation, and inhalation could lead to respiratory issues. Safety standards recommend using personal protective equipment (PPE) like gloves and goggles, and working in a well-ventilated area. Proper disposal is essential to avoid environmental harm, as it is harmful to aquatic life.

How should 4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid (CAS: 1918-02-1) be stored?

4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid (CAS: 1918-02-1) should be stored in a cool, dry place at 2-8°C to maintain stability. It must be kept in airtight containers to prevent moisture and contamination. Avoid exposure to light and ensure storage away from incompatible materials. Proper labeling and adherence to chemical safety guidelines are critical for safe handling and preservation.