3-Methyl-1,3-thiazolidine-2-thione

Basic Information

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CAS Number

1908-87-8

Molecular Formula

C4H7NS2

Molecular Weight

133.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CN1CCSC1=S

InChI

InChI=1S/C4H7NS2/c1-5-2-3-7-4(5)6/h2-3H2,1H3

InChIKey

RGTLAJIDOSPEDH-UHFFFAOYSA-N

LogP

0.9499

Topological Polar Surface Area

3.24 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

91.7

Synonyms & References

English

RHENOGRAN MTT 80
CS-0449032
CHEMBL397404
RHENOCURE CRV
AM84657
1908-87-8
NSC 122616
AKOS015897585
MTT 80
A813452
MFCD00154793
W-109723
Vulkacit crv
UNII-LIX65700J1
SCHEMBL1231315
N-Methyl-2-thiazolidinethione
3-Methylthiazolidine-2-thione
NSC122616
LIX65700J1
3-METHYL-2-THIAZOLIDINETHIONE
FT-0616078
NS00020161
3-methyl-1,3-thiazolidine-2-thione
DTXSID0062054
BDBM50201530
2-Thiazolidinethione, 3-methyl-
3-Methylimidazolidine-2-thione
NSC-122616
EINECS 217-614-1
3-methyl thiazolidine 2-thion
InChI=1/C4H7NS2/c1-5-2-3-7-4(5)6/h2-3H2,1H

MDL Number

MFCD00154793

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 3-Methyl-1,3-thiazolidine-2-thione (CAS: 1908-87-8)?

3-Methyl-1,3-thiazolidine-2-thione (CAS: 1908-87-8) is a colorless crystalline solid with a molecular weight of approximately 140.17 g/mol. It has a low solubility in water (0.5 g/100 mL at 25°C) and is soluble in common organic solvents like ethanol and acetone. It is relatively stable under normal conditions but can undergo ring-opening reactions in the presence of strong acids or bases. The compound is typically used in pharmaceutical and sensor applications.

How is 3-Methyl-1,3-thiazolidine-2-thione (CAS: 1908-87-8) typically synthesized?

3-Methyl-1,3-thiazolidine-2-thione (CAS: 1908-87-8) can be synthesized via the thioetherification of 3-methyl-1,3-thiazolidine-2-one with a thiol. Commonly, this involves the reaction of 3-methyl-1,3-thiazolidine-2-one with a primary thiol in the presence of a base such as sodium hydroxide. The yield is generally good, around 80-90%, and the method is selective and straightforward.

What industries use 3-Methyl-1,3-thiazolidine-2-thione (CAS: 1908-87-8)?

3-Methyl-1,3-thiazolidine-2-thione (CAS: 1908-87-8) is primarily used in the pharmaceutical industry for intermediate synthesis and in sensor applications due to its thioether functionality. It can also be used in polymer synthesis as a crosslinking agent and in the development of new materials for electronic and semiconductor applications.

What precautions should be taken when handling 3-Methyl-1,3-thiazolidine-2-thione (CAS: 1908-87-8)?

When handling 3-Methyl-1,3-thiazolidine-2-thione (CAS: 1908-87-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to prevent inhalation. In case of a spill, immediately clean up with appropriate absorbent material and ensure proper disposal. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.