Lithium 2-methyl-2-propanolate

Basic Information

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CAS Number

1907-33-1

Molecular Formula

C4H9LiO

Molecular Weight

80.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

°C

Boiling Point

68-70 °C

Solubility

Soluble in toluene, hexane, tetrahydrofuran and methyl tert-butyl ether.

Refractive Index

1.52299 (124ºC)

Vapor Pressure

No data available

SMILES

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[Li+].CC(C)(C)[O-]

InChI

InChI=1S/C4H9O.Li/c1-4(2,3)5;/h1-3H3;/q-1;+1

InChIKey

LZWQNOHZMQIFBX-UHFFFAOYSA-N

LogP

1.21540

Complexity

Safety Information

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GHS Hazard Pictograms

H251

H302

H314

Hazard Statement

H251 Self-heating; may catch fire
Self-heating substances and mixtures

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 4.2 Class 4.2

Sensitiveness

Moisture Sensitive

Synonyms & References

English

L0253
Lithium tert-butylate
tBuOLi
tert-Butoxylithium
DTXSID9051828
EINECS 217-611-5
Lithium tert-butanolate
1907-33-1
Lithium t-butoxide, 2 M in THF
MFCD00050479
lithium tbutoxide
AKOS015950735
LiOtBu
tert-Butyl alcohol, lithium salt
2-Methyl-2-propanol lithium salt
lithium-t-butoxide
AKOS015841135
FT-0689129
LZWQNOHZMQIFBX-UHFFFAOYSA-N
Lithium t-butoxide, 2.2M in THF
Lithium tert-butoxide
t-BuOLi
D78330
EN300-182652
tert-BuOLi
lithium;2-methylpropan-2-olate
lithium t-butoxide
Lithium tert -butanolate
Lithium t-butoxide, 1M in THF
lithium tertbutoxide
2-Propanol, 2-methyl-, lithium salt

MDL Number

MFCD00050479

Customs Code

2905143000

FAQ

What is Lithium 2-methyl-2-propanolate (CAS: 1907-33-1)?

Lithium 2-methyl-2-propanolate (CAS: 1907-33-1) is a lithium alkoxide compound with the chemical formula C4H9OLi. It is derived from 2-methyl-2-propanol (tert-butyl alcohol) and is known for its strong basicity and reactivity. This compound is commonly used in organic synthesis due to its ability to act as a nucleophile and its role in forming carbon-lithium bonds. It appears as a white solid and is soluble in polar solvents like ethanol and diethyl ether.

What are the main uses of Lithium 2-methyl-2-propanolate (CAS: 1907-33-1)?

Lithium 2-methyl-2-propanolate (CAS: 1907-33-1) is primarily used in pharmaceuticals as a synthetic intermediate for drug development. In industrial applications, it serves as a catalyst in polymerization reactions and organic synthesis processes. It is also employed in research for creating complex organic molecules and in the production of specialty chemicals. Its unique reactivity makes it valuable in reactions requiring strong bases or alkoxide functionality.

Is Lithium 2-methyl-2-propanolate (CAS: 1907-33-1) safe?

Lithium 2-methyl-2-propanolate (CAS: 1907-33-1) requires careful handling due to its corrosive nature and reactivity with moisture. It is classified as a hazardous substance, with potential toxicity via inhalation or skin contact. Safety precautions include using appropriate personal protective equipment (PPE), working in a well-ventilated area, and avoiding exposure to water. Adherence to safety standards like OSHA guidelines is essential to minimize risks during storage, use, and disposal.

How should Lithium 2-methyl-2-propanolate (CAS: 1907-33-1) be stored?

Lithium 2-methyl-2-propanolate (CAS: 1907-33-1) should be stored in a cool, dry place, away from moisture and incompatible materials. It is moisture-sensitive and requires airtight, sealed containers to maintain stability. Storage at ambient temperature (15-25°C) is recommended, with protection from light and air. Always keep it in a well-ventilated area and follow guidelines for handling reactive chemical compounds to ensure safety and longevity.