2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one | CAS No. 188399-46-4

2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one

Basic Information

CAS Number

188399-46-4

Molecular Formula

C12H15N5O3

Molecular Weight

277.28 g/mol

AD

Basic Physical Properties

C=C1C(CC(C1CO)O)N2C=NC3=C2N=C(NC3=O)N

InChI

InChI=1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)

InChIKey

QDGZDCVAUDNJFG-UHFFFAOYSA-N

LogP

-0.8278000000000001

Topological Polar Surface Area

130.05 Ų

Hydrogen Bond Donor/Acceptor

5 / 8

Complexity

480

Synonyms & References

English

  • 2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one
  • ent-Entecavir
  • 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-Purin-6-one
  • (1R,3S,4R)-Entecavir
  • AK103067
  • ANW-65144
  • CHEMBL440792
  • CTK8C0707
  • FT-0667866
  • KB-78114
  • SC1449
  • Entecavir Enantiomer (1R,3S,4R)
  • 2-amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one
  • 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-
  • [1R-(1α,3α,4β)]-2-AMino-1,9-dihydro-9-[4-hydroxy-3-(hydroxyMethyl)-2-Methylenecyclopentyl]-6H-purin-6-one
  • 2-Amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-Purin-6-one; [1R-(1a,3a,4ss)]-2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one;
  • 2-amino-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one
  • DTXSID80658124
  • 6H-PURIN-6-ONE, 2-AMINO-1,9-DIHYDRO-9-[(1R,3S,4R)-4-HYDROXY-3-(HYDROXYMETHYL)-2-METHYLENECYCLOPENTYL]-
  • 2-Amino-9-((1R,3S,4R)-rel-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one
  • 2-amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2- methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one
  • 2-Amino-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3,9-dihydro-6H-purin-6-one
  • 1333204-94-6
  • 2-AMINO-9-[(1R,3S,4R)-4-HYDROXY-3-(HYDROXYMETHYL)-2-METHYLIDENECYCLOPENTYL]-1H-PURIN-6-ONE
  • 188399-46-4
  • Entecavir Impurity 07
  • AKOS016843345
  • 2-amino-1,9-dihydro-9-((1r,3s,4r)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-6h-purin-6-one
  • AC-36784

MDL Number

MFCD16660347

FAQ

What is 2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one (CAS: 188399-46-4)?

2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one (CAS: 188399-46-4) is an organic compound with a purine backbone and a complex side chain. It is a white solid with a molecular weight of approximately 370.36 g/mol. This compound is stable under normal conditions but can react with strong acids or bases.

What are the main uses of 2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one (CAS: 188399-46-4)?

This compound is primarily used in pharmaceutical research as a potential therapeutic agent. It has shown promise in the treatment of certain neurological disorders and may have applications in cancer research. Further clinical trials are needed to fully determine its efficacy and safety.

Is 2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one (CAS: 188399-46-4) safe?

2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one (CAS: 188399-46-4) is generally safe when handled with appropriate precautions. It should be kept away from strong acids and bases to prevent degradation. Protective equipment such as gloves and goggles should be used to avoid direct contact with the skin or eyes.

How should 2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one (CAS: 188399-46-4) be stored?

2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one (CAS: 188399-46-4) should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container and protected from moisture. Storage at temperatures below 25°C is recommended to maintain its stability.

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