Abacavir sulfate

Basic Information

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CAS Number

188062-50-2

Molecular Formula

C28H38N12O6S

Molecular Weight

670.76 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

222-225°C

Boiling Point

636°C at 760 mmHg

Density

No data available

Flash Point

No data available

Solubility

H2O: ≥17mg/mL

Vapor Pressure

No data available

SMILES

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C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)CO.C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)CO.OS(=O)(=O)O

InChI

InChI=1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1

InChIKey

WMHSRBZIJNQHKT-FFKFEZPRSA-N

LogP

1.5318000000000007

Topological Polar Surface Area

278.36 Å²

Hydrogen Bond Donor/Acceptor

10 / 18

Complexity

496

Safety Information

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Hazard Statement

H351 Suspected of causing cancer
Carcinogenicity

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

1423331-68-3
UNII-J220T4J9Q2
Abacavir sulfate [USAN]
NSC-760063
CHEBI:2361
ABACAVIR SULFATE [USP-RS]
Abacavir sulfate [USAN:USP]
136777-48-5
HMS3714F06
ABACAVIR SULFATE COMPONENT OF TRIZIVIR
Abacavir Hemisulfate
2-CYCLOPENTENE-1-METHANOL, 4-(2-AMINO-6-(CYCLOPROPYLAMINO)-9H-PURIN-9-YL)-, (1S,4R)-, SULFATE (2:1)
Abacavir sulfate, (+/-)-
AS-17843
2-Cyclopentene-1-methanol,4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-,hydrochloride(1:1),(1S,4R)-
J-700139
EN300-257999
ABACAVIR SULFATE [USP MONOGRAPH]
EPZICOM COMPONENT ABACAVIR SULFATE
ABACAVIR SULFATE [JAN]
ABACAVIR SULFATE [VANDF]
DTXCID101324187
Abacavir sulfate racemic
(1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol sulfate (salt) (2:1)
ABACAVIR SULFATE COMPONENT OF TRIUMEQ
ABACAVIR SULFATE [WHO-DD]
((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol hemisulfate
188062-50-2
ABACAVIR SULFATE [ORANGE BOOK]
ABACAVIR SULFATE [HSDB]
ABACAVIR SULFATE [WHO-IP]

MDL Number

MFCD04112763

FAQ

What is Abacavir sulfate (CAS: 188062-50-2)?

Abacavir sulfate is a white crystalline solid used primarily as an antiretroviral drug. Its chemical formula is C17H17N5NaO4S. It is used in combination with other medications to treat HIV infection.

What are the main uses of Abacavir sulfate (CAS: 188062-50-2)?

Abacavir sulfate is mainly used as a treatment for HIV-1 infection. It is often prescribed in combination with other antiretroviral drugs to suppress the virus and slow the progression of the disease.

Is Abacavir sulfate (CAS: 188062-50-2) safe?

Abacavir sulfate is generally considered safe when used as directed. However, it may cause severe hypersensitivity reactions in some individuals. Patients should be monitored closely for any adverse effects and should discontinue use if symptoms such as rash, fever, or vomiting occur.

How should Abacavir sulfate (CAS: 188062-50-2) be stored?

Abacavir sulfate should be stored at a temperature not exceeding 25°C (77°F) and protected from moisture and light. It should be kept in a tightly sealed container to maintain its stability and efficacy. Avoid exposure to extreme temperatures and direct sunlight.