2-(1H-Imidazol-2-yl)pyridine

Basic Information

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CAS Number

18653-75-3

Molecular Formula

C8H7N3

Molecular Weight

145.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Brown to Dark-brown Solid

Melting Point

135-140 °C

Boiling Point

382.8°C at 760 mmHg

Density

1.214

Flash Point

191.5±13.3 °C

Refractive Index

1.61

SMILES

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C1=CC=NC(=C1)C2=NC=CN2

InChI

InChI=1S/C8H7N3/c1-2-4-9-7(3-1)8-10-5-6-11-8/h1-6H,(H,10,11)

InChIKey

SZXUTTGMFUSMCE-UHFFFAOYSA-N

LogP

1.4716999999999998

Topological Polar Surface Area

41.57 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

127

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

2-(2-Pyridyl)imidazole
SY057674
2-Imidazol-2-yl)-pyridine
CHEMBL137663
2-(1H-Imidazol-2-yl)-pyridine
A813054
EN300-60625
2-(1H-Imidazol-2-yl)pyridine, 97%
Z728187802
2-(IMIDAZOL-2-YL)-PYRIDINE
AKOS010225942
DS-6338
2-(2'-pyridyl) imidazole
1H-imidazol-2-ylpyridine
SCHEMBL117383
AB22499
pyridinyl imidazole
A25144
18653-75-3
YSWG043
AMY23472
DTXSID00343363
2-(Pyridyl-2-yl)imidazole
MFCD05863221
CS-W008843
2-(1H-Imidazol-2-yl)pyridine
PYRIDINE, 2-(1H-IMIDAZOL-2-YL)-
2-(2-Imidazolyl)pyridine
2-(1H-Imidazol-2-yl)pyridine #
2-(2 inverted exclamation marka-Pyridyl)imidazole pound>>2-(2-Pyridyl)imidazole pound>> 2-(Imidazol-2-yl)pyridine pound>>2-(Pyridin-2-yl)imidazole pound>> Pyridine,2-imidazol-2-yl- (8Cl)
F1905-7074

MDL Number

MFCD05863221

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-(1H-Imidazol-2-yl)pyridine (CAS: 18653-75-3)?

2-(1H-Imidazol-2-yl)pyridine is a crystalline solid with a molecular weight of approximately 171.15 g/mol. It is slightly soluble in water but highly soluble in organic solvents like ethanol and acetone. Chemically, it is known for its reactivity towards nucleophilic substitution reactions and coordination chemistry. It has application in various industries due to its unique structural features and functional groups.

How is 2-(1H-Imidazol-2-yl)pyridine (CAS: 18653-75-3) typically synthesized?

2-(1H-Imidazol-2-yl)pyridine is synthesized through the condensation reaction between 2-methylimidazole and pyridine. Commonly, this involves a simple multi-step process, where 2-methylimidazole reacts with pyridine under basic conditions to form the desired product. The yield and selectivity of the reaction can be optimized with suitable catalysts and solvents.

What industries use 2-(1H-Imidazol-2-yl)pyridine (CAS: 18653-75-3)?

2-(1H-Imidazol-2-yl)pyridine is used in the pharmaceutical industry for the synthesis of certain drugs, in polymer applications for its catalytic properties, in sensor technology for detecting specific analytes, and in the semiconductor industry due to its electronic properties. Its versatility makes it a valuable compound in these and other specialized fields.

What precautions should be taken when handling 2-(1H-Imidazol-2-yl)pyridine (CAS: 18653-75-3)?

When handling 2-(1H-Imidazol-2-yl)pyridine, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to laboratory safety protocols. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.