3-Azetidinylacetic acid

Basic Information

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CAS Number

183062-92-2

Molecular Formula

C5H9NO2

Molecular Weight

115.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

260 ºC

Flash Point

111 ºC

SMILES

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OC(=O)CC1CNC1

InChI

InChI=1S/C5H9NO2/c7-5(8)1-4-2-6-3-4/h4,6H,1-3H2,(H,7,8)

InChIKey

SCBDSTCOJNNUCN-UHFFFAOYSA-N

LogP

-0.3194999999999999

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Synonyms & References

English

Azetidin-3-yl-acetic acid
2-(azetidin-3-yl)acetic acid
3-Azetidineacetic acid
azetidin-3-ylacetic acid
Azetidine-3-acetic acid
2-(3-azetidinyl)acetic acid
2-(AZETIDIN-3YL)ACETIC ACID
azetidine-3-ylacetic acid

MDL Number

MFCD09998940

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 3-Azetidinylacetic acid (CAS: 183062-92-2)?

3-Azetidinylacetic acid is a colorless crystalline solid with a molecular weight of approximately 140.16 g/mol. It is slightly soluble in water and moderately soluble in ethanol. Chemically, it is reactive towards nucleophiles and can undergo esterification and amide formation reactions.

How is 3-Azetidinylacetic acid (CAS: 183062-92-2) typically synthesized?

3-Azetidinylacetic acid can be synthesized through the condensation of 3-azetidinone and acetic acid in the presence of a suitable catalyst, such as sodium acetate or sodium hydroxide, leading to a yield of around 70-80%. The reaction is typically carried out under mild conditions to ensure selectivity and high purity.

What industries use 3-Azetidinylacetic acid (CAS: 183062-92-2)?

3-Azetidinylacetic acid finds applications in the pharmaceutical industry for the synthesis of certain drugs, and in the polymer industry for the development of functional polymers. It is also used in the production of sensors and as a precursor in semiconductor manufacturing.

What precautions should be taken when handling 3-Azetidinylacetic acid (CAS: 183062-92-2)?

When handling 3-Azetidinylacetic acid, wear appropriate personal protective equipment such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation of vapors. Spills should be cleaned up with care, and the material safety data sheet (MSDS) should be consulted for specific spill procedures.